Horizontal gene transfer between different domains of life is increasingly being recognized
as an important evolutionary driver, with the potential to increase the pace of biochemical …

Integrons are bacterial genetic elements that can capture mobile gene cassettes. They are
mostly known for their role in the spread of antibiotic resistance cassettes, contributing …

Integrons are microbial genetic elements that can integrate mobile gene cassettes. They are
mostly known for spreading antibiotic resistance cassettes among human pathogens …

Multiple antibiotic resistances are a major global health threat. The predominant tool for
adaptation in Gram-negative bacteria is the integron. Under stress, it rearranges gene …

Integrons are genetic elements, found among diverse bacteria and archaea, that capture
and rearrange gene cassettes to rapidly generate genetic diversity and drive adaptation …

Abstract Programmed–1 ribosomal frameshifting (PRF) in cardioviruses is activated by the
2A protein, a multi-functional virulence factor that also inhibits cap-dependent translational …

Recombination systems are widely used as bioengineering tools, but their sites have to be
highly similar to a consensus sequence or to each other. To develop a recombination …

Many proteins form dynamic complexes with DNA, RNA, and other proteins, which often
involves protein conformational changes that are key to function. Yet, methods to probe …

Single molecule biophysics experiments have enabled the observation of biomolecules with
a great deal of precision in space and time, eg nucleic acids mechanical properties and …

Optical tweezers are a single-molecule technique that allows probing of intra-and
intermolecular interactions that govern complex biological processes involving molecular …