Recovery from disorders of consciousness: mechanisms, prognosis and emerging therapies

BL Edlow, J Claassen, ND Schiff… - Nature Reviews Neurology, 2021 - nature.com
Substantial progress has been made over the past two decades in detecting, predicting and
promoting recovery of consciousness in patients with disorders of consciousness (DoC) …

Therapeutic interventions in patients with prolonged disorders of consciousness

A Thibaut, N Schiff, J Giacino, S Laureys… - The Lancet …, 2019 - thelancet.com
The management of patients with severe brain injuries and prolonged disorders of
consciousness raises important issues particularly with respect to their therapeutic options …

Thalamic deep brain stimulation in traumatic brain injury: a phase 1, randomized feasibility study

ND Schiff, JT Giacino, CR Butson, EY Choi, JL Baker… - Nature medicine, 2023 - nature.com
Converging evidence indicates that impairments in executive function and information-
processing speed limit quality of life and social reentry after moderate-to-severe traumatic …

Are the neural correlates of consciousness in the front or in the back of the cerebral cortex? Clinical and neuroimaging evidence

M Boly, M Massimini, N Tsuchiya… - Journal of …, 2017 - Soc Neuroscience
The role of the frontal cortex in consciousness remains a matter of debate. In this
Perspective, we will critically review the clinical and neuroimaging evidence for the …

Robust EEG-based cross-site and cross-protocol classification of states of consciousness

DA Engemann, F Raimondo, JR King, B Rohaut… - Brain, 2018 - academic.oup.com
Determining the state of consciousness in patients with disorders of consciousness is a
challenging practical and theoretical problem. Recent findings suggest that multiple markers …

[CITATION][C] Consciousness and the Brain: Deciphering How the Brain Codes Our Thoughts

S Dehaene - 2014 - books.google.com
WINNER OF THE 2014 BRAIN PRIZE From the acclaimed author of Reading in the Brain
and How We Learn, a breathtaking look at the new science that can track consciousness …

The thalamus integrates the macrosystems of the brain to facilitate complex, adaptive brain network dynamics

JM Shine - Progress in neurobiology, 2021 - Elsevier
The human brain is a complex, adaptive system comprised of billions of cells with trillions of
connections. The interactions between the elements of the system oppose this seemingly …

Stratification of unresponsive patients by an independently validated index of brain complexity

S Casarotto, A Comanducci, M Rosanova… - Annals of …, 2016 - Wiley Online Library
Objective Validating objective, brain‐based indices of consciousness in behaviorally
unresponsive patients represents a challenge due to the impossibility of obtaining …

Disorders of consciousness after acquired brain injury: the state of the science

JT Giacino, JJ Fins, S Laureys, ND Schiff - Nature Reviews Neurology, 2014 - nature.com
The concept of consciousness continues to defy definition and elude the grasp of
philosophical and scientific efforts to formulate a testable construct that maps to human …

Clinical and advanced neurophysiology in the prognostic and diagnostic evaluation of disorders of consciousness: review of an IFCN-endorsed expert group

A Comanducci, M Boly, J Claassen, M De Lucia… - Clinical …, 2020 - Elsevier
The analysis of spontaneous EEG activity and evoked potentials is a cornerstone of the
instrumental evaluation of patients with disorders of consciousness (DoC). The past few …