[HTML][HTML] The role of matrix metalloproteinases in infectious corneal ulcers

C García-López, M Rodríguez-Calvo-de-Mora… - Survey of …, 2023 - Elsevier
During infectious keratitis, the production of collagenolytic and inflammatory substances,
along with increased corneal matrix metalloproteinase (MMP) activity, induces the …

Intra-articular injection of ascorbic acid enhances microfracture-mediated cartilage repair

Z Chen, S Zhang, P Duan, Z Yin, S Dong, R Pang… - Scientific Reports, 2024 - nature.com
Previous studies have confirmed that ascorbic acid (AA) can promote cartilage repair and
improve cartilage differentiation in bone marrow mesenchymal stem cells. However, the use …

Evaluation of CRISPR/Cas9 mediated TGIF gene editing to inhibit corneal fibrosis in vitro

R Tripathi, NR Sinha, D Kempuraj, PK Balne… - Experimental Eye …, 2022 - Elsevier
Corneal wound healing is influenced by many factors including transcriptional co-repressors
and co-activators. Interactions of co-activators and co-repressors with Smads influence …

Vitamin C Regulates the Profibrotic Activity of Fibroblasts in In Vitro Replica Settings of Myocardial Infarction

Y Xu, H Zheng, P Nilcham, O Bucur, F Vogt… - International Journal of …, 2023 - mdpi.com
Extracellular collagen remodeling is one of the central mechanisms responsible for the
structural and compositional coherence of myocardium in patients undergoing myocardial …

Sulfur mustard corneal injury is associated with alterations in the epithelial basement membrane and stromal extracellular matrix

LB Joseph, MK Gordon, P Zhou, RA Hahn… - … and molecular pathology, 2022 - Elsevier
Abstract Sulfur mustard (SM; bis (2-chloroethyl) sulfide) is a highly reactive bifunctional
alkylating agent synthesized for chemical warfare. The eyes are particularly sensitive to SM …

Washing with buffered vitamin C after corrosive chemical (sodium hypochlorite) exposure reduces ocular depth of injury

S Lebrun, L Nguyen, J Romero, R Chan - Toxicology in Vitro, 2025 - Elsevier
Chemical eye injuries occur in home, industrial, and military settings. The standard
recommended treatment after exposure of the eyes to chemical toxins is washing with tap …

Differences in change of post‐operative antioxidant levels between laser‐assisted lenticule extraction and femtosecond laser in situ keratomileusis

HC Chen, SF Yang, CY Lee, YJ Hsueh… - Journal of Cellular …, 2024 - Wiley Online Library
To evaluate the change of total antioxidant capacity (TAC) and ascorbic acid (AA) between
femtosecond laser in situ keratomileusis (FS‐LASIK) and laser‐assisted lenticule extraction …

Anti‐fibrotic effects of lisinopril (ACE inhibitor) and fasudil (ROCK inhibitor) in combination for canine corneal fibrosis in vitro

BL Routh, R Tripathi, E Giuliano, P Lu**… - Veterinary …, 2024 - Wiley Online Library
Background Corneal fibrosis is a leading cause of blindness in mammalian species and
may result in compromised performance in sports and daily functions. This study evaluated …

[HTML][HTML] Modulators of corneal wound healing–Where do we stand?

M Vanathi - Indian Journal of Ophthalmology, 2024 - journals.lww.com
An enhanced understanding of corneal physiology and the fibrotic molecular pathways
influencing corneal clarity has facilitated innovative research aimed at countering corneal …

Differences in change of post-operative antioxidant levels between laser-assisted lenticule extraction and femtosecond laser in situ keratomileusis

C Hung-Chi, SF Yang, L Chia-Yi… - Journal of Cellular …, 2024 - search.proquest.com
To evaluate the change of total antioxidant capacity (TAC) and ascorbic acid (AA) between
femtosecond laser in situ keratomileusis (FS-LASIK) and laser-assisted lenticule extraction …