The delivery of medical agents to a specific diseased tissue or cell is critical for diagnosing
and treating patients. Nanomaterials are promising vehicles to transport agents that include …

Nanoparticles from natural and anthropogenic sources are abundant in the environment,
thus human exposure to nanoparticles is inevitable. Due to this constant exposure, it is …

Effective delivery of therapeutic and diagnostic nanoparticles is dependent on their ability to
accumulate in diseased tissues. However, most nanoparticles end up in liver macrophages …

The successful delivery of nanoparticles to solid tumors depends on their ability to pass
through blood vessels and into the tumor microenvironment. Here, we discovered a subset …

Nanoparticles need to navigate a complex microenvironment to target cells in solid tumors
after extravasation. Diffusion is currently the accepted primary mechanism for nanoparticle …

Bioimaging enables the spatiotemporal visualization of biological processes at various
scales empowered by a range of different imaging modalities and contrast agents …

Nanoparticle transport across tumor blood vessels is a key step in nanoparticle delivery to
solid tumors. However, the specific pathways and mechanisms of this nanoparticle delivery …

Nanoparticle modification with poly (ethylene glycol)(PEG) is a widely used surface
engineering strategy in nanomedicine. However, since the artificial PEG polymer may …

Three-dimensional (3D) visualization of tumor vasculature is a key factor in accurate
evaluation of RNA interference (RNAi)-based antiangiogenic nanomedicine, a promising …

Most nanomedicines require efficient in vivo delivery to elicit meaningful diagnostic and
therapeutic effects. However, en route to their intended tissues, systemically administered …