Pulmonary surfactant is an essential lipid-protein complex that stabilizes the respiratory units
(alveoli) involved in gas exchange. Quantitative or qualitative derangements in surfactant …

Abstract I. Introduction 38 A. Protein Conformations and Dynamics 38 B. Protein‐Energy
Landscapes: The Folding Problem and Dynamics in the Native State 38 1. Protein …

The hydrophobic surfactant proteins, SP-B and SP-C, have important roles in surfactant
function. The importance of these proteins in normal lung function is highlighted by the lung …

Abstract Surfactant protein C (SP-C) is a hydrophobic 35-amino acid peptide that co-isolates
with the phospholipid fraction of lung surfactant. SP-C represents a structurally and …

The solvent-accessible surface area of proteins is important in biological function for many
reasons, including protein–protein interactions, protein folding, and catalytic sites. Here we …

Abstract Treatment of neonatal respiratory distress syndrome (RDS) using animal‐derived
lung surfactant preparations has reduced the mortality of handling premature infants with …

In the respiratory tract, recognition of bacterial endotoxin (lipopolysacharide, LPS) is a
critical step of the innate host defense system directed against invading pathogens …

Pulmonary alveolar proteinosis (PAP) is a rare disorder characterised histologically by an
intra-alveolar accumulation of fine granular eosinophilic and periodic acid-Schiff positive …

Pulmonary surfactant is a lipid-protein complex that coats the interior of the alveoli and
enables the lungs to function properly. Upon its synthesis, lung surfactant adsorbs at the …

Summing up almost a decade of biomedical research, this topical and eagerly awaited
handbook is the first reference on the topic to incorporate recent breakthroughs in amyloid …