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How viral and intracellular bacterial pathogens reprogram the metabolism of host cells to allow their intracellular replication
Viruses and intracellular bacterial pathogens (IBPs) have in common the need of suitable
host cells for efficient replication and proliferation during infection. In human infections, the …
host cells for efficient replication and proliferation during infection. In human infections, the …
CircRNAs in anticancer drug resistance: recent advances and future potential
T Xu, M Wang, L Jiang, L Ma, L Wan, Q Chen, C Wei… - Molecular cancer, 2020 - Springer
CircRNAs are a novel class of RNA molecules with a unique closed continuous loop
structure. CircRNAs are abundant in eukaryotic cells, have unique stability and tissue …
structure. CircRNAs are abundant in eukaryotic cells, have unique stability and tissue …
Lycopene from tomatoes and tomato products exerts renoprotective effects by ameliorating oxidative stress, apoptosis, pyroptosis, fibrosis, and inflammatory injury in …
X Gao, B Lin, C Chen, Z Fang, J Yang, S Wu… - Food & Function, 2024 - pubs.rsc.org
Several mechanisms underlying nephrolithiasis, one of the most common urological
diseases, involve calcium oxalate formation, including oxidative stress, inflammatory …
diseases, involve calcium oxalate formation, including oxidative stress, inflammatory …
[HTML][HTML] The role of voltage-dependent anion channel in mitochondrial dysfunction and human disease
JT Varughese, SK Buchanan, AS Pitt - Cells, 2021 - mdpi.com
The voltage-dependent anion channel (VDAC) is a β-barrel membrane protein located in the
outer mitochondrial membrane (OMM). VDAC has two conductance states: an open anion …
outer mitochondrial membrane (OMM). VDAC has two conductance states: an open anion …
Chlamydial infection from outside to inside
A Gitsels, N Sanders, D Vanrompay - Frontiers in Microbiology, 2019 - frontiersin.org
Chlamydia are obligate intracellular bacteria, characterized by a unique biphasic
developmental cycle. Specific interactions with the host cell are crucial for the bacteria's …
developmental cycle. Specific interactions with the host cell are crucial for the bacteria's …
[HTML][HTML] Fibroblast growth factor 7 alleviates myocardial infarction by improving oxidative stress via PI3Kα/AKT-mediated regulation of Nrf2 and HXK2
Acute myocardial infarction (MI) triggers oxidative stress, which worsen cardiac function,
eventually leads to remodeling and heart failure. Unfortunately, effective therapeutic …
eventually leads to remodeling and heart failure. Unfortunately, effective therapeutic …
[HTML][HTML] aFGF alleviates diabetic endothelial dysfunction by decreasing oxidative stress via Wnt/β-catenin-mediated upregulation of HXK2
Vascular complications of diabetes are a serious challenge in clinical practice, and effective
treatments are an unmet clinical need. Acidic fibroblast growth factor (aFGF) has potent anti …
treatments are an unmet clinical need. Acidic fibroblast growth factor (aFGF) has potent anti …
Chlamydia trachomatis infection: their potential implication in the etiology of cervical cancer
Pathogenic bacterial strains can alter the normal function of cells and induce different levels
of inflammatory responses that are connected to the development of different diseases, such …
of inflammatory responses that are connected to the development of different diseases, such …
Bacteria as a double-action sword in cancer
Bacteria have long been known as one of the primary causative agents of cancer, however,
recent studies suggest that they can be used as a promising agent in cancer therapy …
recent studies suggest that they can be used as a promising agent in cancer therapy …
Chlamydia trachomatis inhibits apoptosis in infected cells by targeting the pro-apoptotic proteins Bax and Bak
Apoptosis acts in defense against microbial infection, and many infectious agents have
developed strategies to inhibit host cell apoptosis. The human pathogen Chlamydia …
developed strategies to inhibit host cell apoptosis. The human pathogen Chlamydia …