Raman spectroscopy has made significant progress in biosensing and clinical research.
Here, we describe how surface-enhanced Raman spectroscopy (SERS) assisted with …

Over the last 60 years, soil microbiologists have accumulated a wealth of experimental data
showing that the bulk, macroscopic parameters (eg, granulometry, pH, soil organic matter …

The conventional microbial cell analyses are mostly population-averaged methods that
conceal the characteristics of single-cell in the community. Single-cell analysis can provide …

Rapid detection of food-borne pathogens in early food contamination is a permanent topic to
ensure food safety and prevent public health problems. Raman spectroscopy, a label-free …

Antimicrobial resistance (AMR) in soils represents a serious risk to human health through
the food chain and human–nature contact. However, the active antibiotic-resistant bacteria …

Although apoptosis and necrosis have distinct features, the identification and discrimination
of apoptotic and necrotic cell death in vitro is challenging. Immunocytological and …

Rare cells are low-abundance cells in a much larger population of background cells.
Conventional benchtop techniques have limited capabilities to isolate and analyze rare cells …

Highlights•Single cell Raman spectra (SCRS) are label-free and intrinsic biochemical
profiles of single microbial cells.•A number of bands of SCRS shift if cells are labeled with …

In his 1665 treatise, Micrographia, Robert Hooke described the many observations he had
made using a microscope, including compartment-like structures in cork samples that he …

Live single-cell mass spectrometry (live MS) provides a mass spectrum that shows
thousands of metabolite peaks from a single live plant cell within minutes. By using an …