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[HTML][HTML] Podophyllotoxin: recent advances in the development of hybridization strategies to enhance its antitumoral profile
Podophyllotoxin is a naturally occurring cyclolignan isolated from rhizomes of Podophyllum
sp. In the clinic, it is used mainly as an antiviral; however, its antitumor activity is even more …
sp. In the clinic, it is used mainly as an antiviral; however, its antitumor activity is even more …
Improving Properties of Podophyllic Aldehyde-Derived Cyclolignans: Design, Synthesis and Evaluation of Novel Lignohydroquinones, Dual-Selective Hybrids against …
New lignohydroquinone conjugates (L-HQs) were designed and synthesized using the
hybridization strategy, and evaluated as cytotoxics against several cancer cell lines. The L …
hybridization strategy, and evaluated as cytotoxics against several cancer cell lines. The L …
Design, Synthesis, and In Vitro Anticancer Activity of Triazolyl Analogs of Abietic Acid
A series of abietic acid analogs modified with a triazole moiety were synthesized using
Huisgen 1, 3-dipolar cycloaddition in order to obtain potent antitumor agents. The …
Huisgen 1, 3-dipolar cycloaddition in order to obtain potent antitumor agents. The …