Domain-specific languages (DSLs) are able to provide intuitive high-level abstractions that
are easy to work with while attaining better performance than general-purpose languages …

Secure multiparty computation (MPC) is a cryptographic tool that allows computation on top
of sensitive biomedical data without revealing private information to the involved entities …

We live in a new Cambrian Explosion of hardware devices. The end of conventional
processor scaling has driven research and industry practice to explore a new generation of …

Fig. 1| The Seq programming language. a, Conceptual comparison of Seq, python and C++.
Seq combines the high performance of C++ with the programming ease and clarity of …

This paper presents OpenCilk, an open-source software infrastructure for task-parallel
programming that allows for substantial code reuse and easy exploration of design choices …

Haplotype reconstruction of distant genetic variants remains an unsolved problem due to the
short-read length of common sequencing data. Here, we introduce HapTree-X, a …

Motivation The increasing availability of high-quality genome assemblies raised interest in
the characterization of genomic architecture. Major architectural elements, such as common …

The continuous growth of generated sequencing data leads to the development of a variety
of associated bioinformatics tools. However, many of them are not able to fully exploit the …

Compiled Domain Specific Languages are taking over various high-performance domains
because of their ability to exploit the domain knowledge and apply optimizations that …

Dynamic programming (DP) is a fundamental algorithmic strategy that decomposes large
problems into manageable subproblems. It is a cornerstone of many important …