The term 'mechanosensation'describes the capacity of cells to translate mechanical stimuli
into the coordinated regulation of intracellular signals, cellular function, gene expression …

Physical forces are ubiquitous in biological processes across scales and diverse contexts.
This review highlights the significance of mechanical forces in nervous system development …

Rationale: One goal of cardiac tissue engineering is the generation of a living, human pump
in vitro that could replace animal models and eventually serve as an in vivo therapeutic …

During nervous system development, neurons extend axons along well-defined pathways.
The current understanding of axon pathfinding is based mainly on chemical signaling …

The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …

Whether cell forces or extracellular matrix (ECM) can impact genome integrity is largely
unclear. Here, acute perturbations (∼ 1 h) to actomyosin stress or ECM elasticity cause …

All cells sense and integrate mechanical and biochemical cues from their environment to
orchestrate organismal development and maintain tissue homeostasis …

Tissue physical properties depend on the cells that make the tissue and also seem to be
affected by tissue use. For example, muscle, cartilage, and bone, when suitably exercised …

Stem cells mechanosense the stiffness of their microenvironment, which impacts
differentiation. Although tissue hydration anti-correlates with stiffness, extracellular matrix …

Blood and lymphatic vessels are lined by endothelial cells which constantly interact with
their luminal and abluminal extracellular environments. These interactions confer physical …