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[HTML][HTML] Natural history of hepatitis C
RH Westbrook, G Dusheiko - Journal of hepatology, 2014 - Elsevier
There has long been evidence that hepatitis C can lead to persistent infection in a high
proportion of infected individuals, and can progress to chronic liver disease, cirrhosis and …
proportion of infected individuals, and can progress to chronic liver disease, cirrhosis and …
Cellular and molecular mechanisms of fibrosis
Fibrosis is defined by the overgrowth, hardening, and/or scarring of various tissues and is
attributed to excess deposition of extracellular matrix components including collagen …
attributed to excess deposition of extracellular matrix components including collagen …
Fibrotic disease and the TH1/TH2 paradigm
Tissue fibrosis (scarring) is a leading cause of morbidity and mortality. Current treatments for
fibrotic disorders, such as idiopathic pulmonary fibrosis, hepatic fibrosis and systemic …
fibrotic disorders, such as idiopathic pulmonary fibrosis, hepatic fibrosis and systemic …
[PDF][PDF] Chronic hepatitis C virus (HCV) disease burden and cost in the United States
Hepatitis C virus (HCV) infection is a leading cause of cirrhosis, hepatocellular carcinoma,
and liver transplantation. A better understanding of HCV disease progression and the …
and liver transplantation. A better understanding of HCV disease progression and the …
[HTML][HTML] Cytokine mediated tissue fibrosis
Acute inflammation is a recognised part of normal wound healing. However, when
inflammation fails to resolve and a chronic inflammatory response is established this …
inflammation fails to resolve and a chronic inflammatory response is established this …
[PDF][PDF] Noninvasive assessment of liver fibrosis by measurement of stiffness in patients with chronic hepatitis C
Liver fibrosis is the main predictor of the progression of chronic hepatitis C, and its
assessment by liver biopsy (LB) can help determine therapy. However, biopsy is an invasive …
assessment by liver biopsy (LB) can help determine therapy. However, biopsy is an invasive …
Viral hepatitis B
More than 400 million people worldwide are chronically infected by the hepatitis B virus. The
virus is responsible for more than 300000 cases of liver cancer every year and for similar …
virus is responsible for more than 300000 cases of liver cancer every year and for similar …
Viral infection and iron metabolism
Fundamental cellular operations, including DNA synthesis and the generation of ATP,
require iron. Viruses hijack cells in order to replicate, and efficient replication needs an iron …
require iron. Viruses hijack cells in order to replicate, and efficient replication needs an iron …
[HTML][HTML] Viruses associated with human cancer
It is estimated that viral infections contribute to 15–20% of all human cancers. As obligatory
intracellular parasites, viruses encode proteins that reprogram host cellular signaling …
intracellular parasites, viruses encode proteins that reprogram host cellular signaling …
Oxidative and nitrative DNA damage in animals and patients with inflammatory diseases in relation to inflammation-related carcinogenesis
S Kawanishi, Y Hiraku, S Pinlaor, N Ma - 2006 - degruyter.com
Infection and chronic inflammation are proposed to contribute to carcinogenesis through
inflammation-related mechanisms. Infection with hepatitis C virus, Helicobacter pylori and …
inflammation-related mechanisms. Infection with hepatitis C virus, Helicobacter pylori and …