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The immune epitope database and analysis resource in epitope discovery and synthetic vaccine design
The task of epitope discovery and vaccine design is increasingly reliant on bioinformatics
analytic tools and access to depositories of curated data relevant to immune reactions and …
analytic tools and access to depositories of curated data relevant to immune reactions and …
Exploring Klebsiella pneumoniae capsule polysaccharide proteins to design multiepitope subunit vaccine to fight against pneumonia
Background Klebsiella pneumoniae is an emerging human pathogen causing neonatal lung
disease, catheter-associated infections, and nosocomial outbreaks with high fatality rates …
disease, catheter-associated infections, and nosocomial outbreaks with high fatality rates …
Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination
INTRODUCTION The clinical manifestations of COVID-19 vary from asymptomatic infection
to respiratory failure. Severe disease courses are primarily associated with advanced age …
to respiratory failure. Severe disease courses are primarily associated with advanced age …
Identifying specificity groups in the T cell receptor repertoire
T cell receptor (TCR) sequences are very diverse, with many more possible sequence
combinations than T cells in any one individual,,,. Here we define the minimal requirements …
combinations than T cells in any one individual,,,. Here we define the minimal requirements …
Akkermansia muciniphila induces intestinal adaptive immune responses during homeostasis
Intestinal adaptive immune responses influence host health, yet only a few intestinal
bacteria species that induce cognate adaptive immune responses during homeostasis have …
bacteria species that induce cognate adaptive immune responses during homeostasis have …
IEDB-AR: immune epitope database—analysis resource in 2019
Abstract The Immune Epitope Database Analysis Resource (IEDB-AR, http://tools. iedb. org/)
is a companion website to the IEDB that provides computational tools focused on the …
is a companion website to the IEDB that provides computational tools focused on the …
Predicting HLA class II antigen presentation through integrated deep learning
Accurate prediction of antigen presentation by human leukocyte antigen (HLA) class II
molecules would be valuable for vaccine development and cancer immunotherapies …
molecules would be valuable for vaccine development and cancer immunotherapies …
[HTML][HTML] Heterogeneous tumor-immune microenvironments among differentially growing metastases in an ovarian cancer patient
We present an exceptional case of a patient with high-grade serous ovarian cancer, treated
with multiple chemotherapy regimens, who exhibited regression of some metastatic lesions …
with multiple chemotherapy regimens, who exhibited regression of some metastatic lesions …
Contriving multi-epitope subunit of vaccine for COVID-19: immunoinformatics approaches
R Dong, Z Chu, F Yu, Y Zha - Frontiers in immunology, 2020 - frontiersin.org
COVID-19 has recently become the most serious threat to public health, and its prevalence
has been increasing at an alarming rate. The incubation period for the virus is~ 1–14 days …
has been increasing at an alarming rate. The incubation period for the virus is~ 1–14 days …
A first-in-human germline-targeting HIV nanoparticle vaccine induced broad and publicly targeted helper T cell responses
The engineered outer domain germline targeting version 8 (eOD-GT8) 60-mer nanoparticle
was designed to prime VRC01-class HIV-specific B cells that would need to be matured …
was designed to prime VRC01-class HIV-specific B cells that would need to be matured …