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Dendrimers in vaccine delivery: Recent progress and advances
Dendrimers are well-defined, highly branched, multivalent and monodisperse molecules
which host a range of attractive, yet functional, chemical and biological characteristics. A …
which host a range of attractive, yet functional, chemical and biological characteristics. A …
Peptide dendrimer-based antibacterial agents: synthesis and applications
Pathogenic bacteria cause the deaths of millions of people every year. With the
development of antibiotics, hundreds and thousands of people's lives have been saved …
development of antibiotics, hundreds and thousands of people's lives have been saved …
[HTML][HTML] Therapeutic potential of polypeptide-based conjugates: rational design and analytical tools that can boost clinical translation
The clinical success of polypeptides as polymeric drugs, covered by the umbrella term
“polymer therapeutics,” combined with related scientific and technological breakthroughs …
“polymer therapeutics,” combined with related scientific and technological breakthroughs …
Functionalized branched polymers: promising immunomodulatory tools for the treatment of cancer and immune disorders
Well-defined synthetic branched nanostructures form an emerging subclass of
macromolecular structures whose 3D structure and multivalency offer unique opportunities …
macromolecular structures whose 3D structure and multivalency offer unique opportunities …
Nanotechnology approaches to improving cancer immunotherapy
Cancer immunotherapy is a powerful, growing treatment approach to cancer that can be
combined with chemotherapy, radiotherapy, and oncosurgery. Modulating the immune …
combined with chemotherapy, radiotherapy, and oncosurgery. Modulating the immune …
[HTML][HTML] Topological aspects of the design of nanocarriers for therapeutic peptides and proteins
Supramolecular chemistry holds great potential for the design of versatile and safe carriers
for therapeutic proteins and peptides. Nanocarriers can be designed to meet specific criteria …
for therapeutic proteins and peptides. Nanocarriers can be designed to meet specific criteria …
Computer simulation of the structural properties of fatty-acid modified PAMAM dendrimers at pH 5 and 7
C Tu, W Mou, ZL Shen - Journal of Molecular Graphics and Modelling, 2023 - Elsevier
In this work, we performed coarse-grained molecular dynamics (CGMD) simulations of G3,
G4, and G5 polyamidoamine (PAMAM) dendrimers grafting with fatty acid (FTA) chains. The …
G4, and G5 polyamidoamine (PAMAM) dendrimers grafting with fatty acid (FTA) chains. The …
Effect of the lipid composition and cholesterol on the membrane selectivity of low generations PAMAM dendrimers: A molecular dynamics simulation study
Among different nanomaterials, dendrimers stand out because of their inherent broad range
of activity against viruses, bacteria, and cancer cells. Herein, a total of 15 molecular systems …
of activity against viruses, bacteria, and cancer cells. Herein, a total of 15 molecular systems …
An update on the use of molecular modeling in dendrimers design for biomedical applications: are we using its full potential?
M Zloh, TS Barata - Expert Opinion on Drug Discovery, 2020 - Taylor & Francis
Introduction Dendrimers are well-defined hyperbranched polymers built from a variety of
different monomers and with tuneable properties that make them suitable for different …
different monomers and with tuneable properties that make them suitable for different …