Off-label use of medication may be presented in these guidelines if a sufficient level of
evidence shows that it can be considered medically appropriate to a given condition and if …

Myocardial injury after noncardiac surgery is defined by elevated postoperative cardiac
troponin concentrations that exceed the 99th percentile of the upper reference limit of the …

The recommendations listed in this document are, whenever possible, evidence based. An
extensive review was conducted on literature published through March 1, 2020. Searches …

Background The certainty that prehabilitation improves postoperative outcomes is not clear.
The objective of this umbrella review (ie systematic review of systematic reviews) was to …

This narrative review presents a biological rationale and evidence to describe how the
preoperative condition of the patient contributes to postoperative morbidity. Any preoperative …

Importance Perioperative cardiovascular complications occur in 3% of hospitalizations for
noncardiac surgery in the US. This review summarizes evidence regarding cardiovascular …

Background Advancing age is independently associated with poor postoperative outcomes.
The ageing of the general population is a major concern for healthcare providers. Trends in …

Frailty is a multidimensional syndrome characterized by decreased reserve and diminished
resistance to stressors. People with frailty are vulnerable to stressors, and exposure to the …

Background: Preliminary data suggest that preoperative N-terminal pro–B-type natriuretic
peptide (NT-proBNP) may improve risk prediction in patients undergoing noncardiac …

BACKGROUND When considering whether a patient is fit for surgery, a comprehensive
patient assessment represents the first step for an anaesthetist to evaluate the risks …