The deiodinase family of enzymes mediates the activation and inactivation of thyroid
hormone. The role of these enzymes in the regulation of the systemic concentrations of …

Thyroid hormones take major part in normal growth, development and metabolism. Over a
century of research has supported a relationship between thyroid hormones and the …

Thyroid function is central in the control of physiological and pathophysiological processes.
Studies in animal models and human research have determined that thyroid hormones …

BACKGROUND: Tissue homeostasis depends on the balance between cell proliferation and
differentiation. Thyroid hormones (THs), through binding to their nuclear receptors, can …

The endocrine system participates in regulating macrophage maturation, although little is
known about the modulating role of the thyroid hormones. In vitro results demonstrate a …

Parathyroid carcinoma (PaC) is a rare cause of primary hyperparathyroidism. Though the
loss of the oncosuppressor CDC73/HRPT2 gene product, parafibromin, has been involved …

Loss of thyroid hormone receptors (TR) is a common feature in some tumors, although their
role in tumor progression is currently unknown. We show here that expression of TRβ1 in …

Thyroid hormone (l-thyroxine, T4, or 3, 5, 3′-triiodo-l-thyronine, T3) treatment of human
papillary and follicular thyroid cancer cell lines resulted in enhanced cell proliferation …

Abstract Activating Transcription Factor‐2 is a sequence‐specific DNA‐binding protein that
belongs to the bZIP family of proteins and plays diverse roles in the mammalian cells. In …

Background Whereas there is increasing evidence that loss of expression and/or function of
the thyroid hormone receptors (TRs) could result in a selective advantage for tumor …