Cancer is the world's second-leading cause of death, and the involvement of microbes in a
range of diseases, including cancer, is well established. The gut microbiota is known to play …

Chemokines are small proteins that control several tissue functions, including cell
recruitment and activation under homeostatic and inflammatory conditions. CXCL8 …

IL-8, a member of the chemokine family, has been shown to play an important role in tumor
growth, angiogenesis, and metastasis. The objective of this study was to determine the …

Interleukin 8, the first chemokine to be characterized, was discovered nearly ten years ago.
Today, more than 30 human chemokines are known. They are often upregulated in …

The development of oral squamous cell carcinoma (OSCC) is a multistep process requiring
the accumulation of multiple genetic alterations, influenced by a patient's genetic …

The aggressive nature of metastatic human cancer has been shown to be related to
numerous abnormalities in growth factors and their receptors. These perturbations confer a …

In the last decade, several groups have shown a direct correlation between the
inappropriate or ectopic release of interleukin (IL)-8 by tumor cells in vitro and their growth …

A variety of factors have been identified that regulate angiogenesis, including the CXC
chemokine family. The CXC chemokines are a unique family of cytokines for their ability to …

It is unknown why only a minority of circulating tumor cells trapped in lung capillaries form
metastases and involvement of immune cells remains uncertain. A novel model has been …

Interleukin 8 (IL-8) is a member of the alpha chemokine family of cytokines originally
identified as a neutrophil chemoattractant. Recently, we reported that elevated levels of IL-8 …