Membranous nephropathy (MN) is a glomerular disease that can occur at all ages. In adults,
it is the most frequent cause of nephrotic syndrome. In~ 80% of patients, there is no …

More than 10 disease-modifying therapies (DMT) are approved by the European Medicines
Agency (EMA) and the US Food and Drug Administration (FDA) for the treatment of multiple …

Membranous nephropathy (MN) is a rare auto-immune disease where the glomerulus is
targeted by circulating auto-antibodies mostly against podocyte antigens, which results in …

Among all glomerular diseases, membranous nephropathy (MN) is perhaps the one in
which major progress has been made in recent decades, in both the understanding of the …

Membranous nephropathy is the most common cause of primary nephrotic syndrome among
adults. The identification of phospholipase A2 receptor (PLA2R) as target antigen in a …

The specific B-cell depleting anti-CD20 monoclonal antibody rituximab (RTX) is effective in
terms of the treatment of various immune-mediated glomerulopathies. The administration of …

Recurrent glomerular disease after kidney transplant remains an important cause of allograft
failure. Many of the different entities post-transplant still suffer from incomplete knowledge on …

Nephrotic proteinuria is the hallmark of several glomerulonephritis determined by different
pathogenetic mechanisms, including autoimmune, degenerative and inflammatory. Some …

Primary membranous nephropathy (PMN) is one of the common causes of adult-onset
nephrotic syndrome and is characterized by autoantibodies against podocyte antigens …

When first introduced, rituximab (RTX), a chimeric anti-CD20 monoclonal antibody, brought
about an alternative therapeutic paradigm for primary membranous nephropathy (PMN) …