The underestimated role of mitochondria in vitiligo: From oxidative stress to inflammation and cell death
Y Lin, Y Ding, Y Wu, Y Yang, Z Liu… - Experimental …, 2024 - Wiley Online Library
Vitiligo is an acquired depigmentary disorder characterized by the depletion of melanocytes
in the skin. Mitochondria shoulder multiple functions in cells, such as production of ATP …
in the skin. Mitochondria shoulder multiple functions in cells, such as production of ATP …
Trained immunity in the pathogenesis of vitiligo
NF Post, G Ginski, R Peters… - Pigment cell & …, 2023 - Wiley Online Library
Vitiligo is caused by an autoimmune reaction against melanocytes leading to melanocyte
loss. The cause of vitiligo is an interaction between genetic susceptibility and environmental …
loss. The cause of vitiligo is an interaction between genetic susceptibility and environmental …
Recent insights into the role of PPARs in disease
N Wagner, KD Wagner - Cells, 2023 - mdpi.com
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that play
important roles in cell proliferation, differentiation, metabolism, and cancer [1–5]. They were …
important roles in cell proliferation, differentiation, metabolism, and cancer [1–5]. They were …
[HTML][HTML] Markers of metabolic abnormalities in vitiligo patients
While vitiligo is primarily caused by melanocyte deficiency or dysfunction, recent studies
have revealed a notable prevalence of metabolic syndrome (MetS) among patients with …
have revealed a notable prevalence of metabolic syndrome (MetS) among patients with …
Decreased ZMIZ1 suppresses melanogenesis in vitiligo by regulating mTOR/AKT/GSK-3β-mediated glucose uptake
W Lu, Z Chen, H Xu, Z Shen, Z Wu, M Li - In Vitro Cellular & …, 2024 - Springer
The loss of epidermal melanocytes is a distinguishing feature of vitiligo (VIT), a prevalent
and long-lasting skin ailment. While various hypotheses exist to explain the cause of VIT, the …
and long-lasting skin ailment. While various hypotheses exist to explain the cause of VIT, the …
New Insights into the Role of PPARγ in Skin Physiopathology
S Briganti, S Mosca, A Di Nardo, E Flori, M Ottaviani - Biomolecules, 2024 - mdpi.com
Peroxisome proliferator-activated receptor gamma (PPARγ) is a transcription factor
expressed in many tissues, including skin, where it is essential for maintaining skin barrier …
expressed in many tissues, including skin, where it is essential for maintaining skin barrier …
Emerging Role of Fibroblasts in Vitiligo: A Formerly Underestimated Rising Star
Y Wu, Y Yang, Y Lin, Y Ding, Z Liu, L **ang… - Journal of Investigative …, 2024 - Elsevier
Vitiligo is a disfiguring depigmentation disorder characterized by loss of melanocytes.
Although numerous studies have been conducted on the pathogenesis of vitiligo, the …
Although numerous studies have been conducted on the pathogenesis of vitiligo, the …
Melatonin and the Skin: Current Progress and Perspectives for Human Health
AT Slominski, TK Kim, Z Janjetovic… - Journal of Investigative …, 2025 - Elsevier
Skin has the capacity to produce and metabolize melatonin into biologically active
metabolites. These metabolites exert phenotypic activities through receptor-dependent and …
metabolites. These metabolites exert phenotypic activities through receptor-dependent and …
Identification of Upregulating Genes, Transcription Factors, and miRNAs in Vitiligo. In silico Study
Background Depigmentation of specific areas of the skin is a persistent and long-lasting
dermatologic disorder known as vitiligo, stemming from the impairment and disruption of …
dermatologic disorder known as vitiligo, stemming from the impairment and disruption of …
Capsaicin combined with stem cells improved mitochondrial dysfunction in PIG3V cells, an immortalized human vitiligo melanocyte cell line, by inhibiting the HSP70 …
Y Wu, X Wang, J Zhang, S Du, Z Wang, J Li… - Molecular Biology …, 2024 - Springer
Background Vitiligo is a common autoimmune skin disease. Capsaicin has been found to
exert a positive effect on vitiligo treatment, and mesenchymal stem cells (MSCs) are also …
exert a positive effect on vitiligo treatment, and mesenchymal stem cells (MSCs) are also …