The neuropathology of chronic traumatic encephalopathy

AC Mckee, B Abdolmohammadi, TD Stein - Handbook of clinical neurology, 2018 - Elsevier
Chronic traumatic encephalopathy (CTE) is a neurodegenerative tauopathy associated with
repetitive head trauma, including concussion and subconcussion. CTE was first recognized …

Pituitary pathology in traumatic brain injury: a review

A Sav, F Rotondo, LV Syro, CA Serna, K Kovacs - Pituitary, 2019 - Springer
Purpose Traumatic brain injury most commonly affects young adults under the age of 35 and
frequently results in reduced quality of life, disability, and death. In long-term survivors …

Fecal microbiota transfer between young and aged mice reverses hallmarks of the aging gut, eye, and brain

A Parker, S Romano, R Ansorge, A Aboelnour… - Microbiome, 2022 - Springer
Background Altered intestinal microbiota composition in later life is associated with
inflammaging, declining tissue function, and increased susceptibility to age-associated …

Cannabis therapeutics and the future of neurology

EB Russo - Frontiers in integrative neuroscience, 2018 - frontiersin.org
Neurological therapeutics have been hampered by its inability to advance beyond
symptomatic treatment of neurodegenerative disorders into the realm of actual palliation …

Systemic inflammation persists the first year after mild traumatic brain injury: results from the prospective trondheim mild traumatic brain injury study

V Chaban, GJB Clarke, T Skandsen, R Islam… - Journal of …, 2020 - liebertpub.com
Innate immune activation has been attributed a key role in traumatic brain injury (TBI) and
successive morbidity. In mild TBI (mTBI), however, the extent and persistence of innate …

Levels of inflammatory cytokines MCP-1, CCL4, and PD-L1 in CSF differentiate idiopathic normal pressure hydrocephalus from neurodegenerative diseases

M Braun, G Boström, M Ingelsson, L Kilander… - Fluids and Barriers of …, 2023 - Springer
Background Neuroinflammatory processes have been suggested to play a role in the
pathophysiology of neurodegenerative diseases and post-hemorrhagic hydrocephalus, but …

CCL2 is associated with microglia and macrophage recruitment in chronic traumatic encephalopathy

JD Cherry, G Meng, S Daley, W **a, S Svirsky… - Journal of …, 2020 - Springer
Background Neuroinflammation has been implicated in the pathogenesis of chronic
traumatic encephalopathy (CTE), a progressive neurodegenerative disease association with …

Cerebrospinal fluid tau, Aβ, and sTREM2 in Former National Football League Players: Modeling the relationship between repetitive head impacts, microglial activation …

ML Alosco, Y Tripodis, NG Fritts, A Heslegrave… - Alzheimer's & …, 2018 - Elsevier
Introduction Cerebrospinal fluid (CSF) protein analysis may facilitate detection and elucidate
mechanisms of neurological consequences from repetitive head impacts (RHI), such as …

Association of white matter rarefaction, arteriolosclerosis, and tau with dementia in chronic traumatic encephalopathy

ML Alosco, TD Stein, Y Tripodis, AS Chua… - JAMA …, 2019 - jamanetwork.com
Importance Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease
associated with repetitive head impacts, including those from US football, that presents with …

Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology

EN Anderson, AA Morera, S Kour, JD Cherry… - Elife, 2021 - elifesciences.org
Traumatic brain injury (TBI) is a predisposing factor for many neurodegenerative diseases,
including amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD), Parkinson's disease …