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Understanding the immunosuppressive microenvironment of glioma: mechanistic insights and clinical perspectives
Glioblastoma (GBM), the predominant and primary malignant intracranial tumor, poses a
formidable challenge due to its immunosuppressive microenvironment, thereby confounding …
formidable challenge due to its immunosuppressive microenvironment, thereby confounding …
An update on the molecular biology of glioblastoma, with clinical implications and progress in its treatment
E Verdugo, I Puerto, MÁ Medina - Cancer Communications, 2022 - Wiley Online Library
Glioblastoma multiforme (GBM) is the most aggressive and common malignant primary brain
tumor. Patients with GBM often have poor prognoses, with a median survival of∼ 15 months …
tumor. Patients with GBM often have poor prognoses, with a median survival of∼ 15 months …
Glioblastoma therapy: Past, present and future
E Obrador, P Moreno-Murciano… - International journal of …, 2024 - mdpi.com
Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …
Although great efforts have been made by clinicians and researchers, no significant …
[HTML][HTML] Targeting the Warburg effect: A revisited perspective from molecular mechanisms to traditional and innovative therapeutic strategies in cancer
M Liao, D Yao, L Wu, C Luo, Z Wang, J Zhang… - … Pharmaceutica Sinica B, 2024 - Elsevier
Cancer reprogramming is an important facilitator of cancer development and survival, with
tumor cells exhibiting a preference for aerobic glycolysis beyond oxidative phosphorylation …
tumor cells exhibiting a preference for aerobic glycolysis beyond oxidative phosphorylation …
The mechanism of Warburg effect-induced chemoresistance in cancer
C Liu, Y **, Z Fan - Frontiers in oncology, 2021 - frontiersin.org
Although chemotherapy can improve the overall survival and prognosis of cancer patients,
chemoresistance remains an obstacle due to the diversity, heterogeneity, and adaptability to …
chemoresistance remains an obstacle due to the diversity, heterogeneity, and adaptability to …
Molecular targeted therapy: a new avenue in glioblastoma treatment
O El Atat, R Naser, M Abdelkhalek… - Oncology …, 2022 - spandidos-publications.com
Glioblastoma, also referred to as glioblastoma multiforme (GBM), is grade IV astrocytoma
characterized by being fast-growing and the most aggressive brain tumor. In adults, it is the …
characterized by being fast-growing and the most aggressive brain tumor. In adults, it is the …
[HTML][HTML] Role of oxidative stress in metabolic reprogramming of brain cancer
Simple Summary According to Globocan 2020 data, approximately 308,102 new cases of
brain cancer and central nervous system (CNS) cancers were reported worldwide, with …
brain cancer and central nervous system (CNS) cancers were reported worldwide, with …
The expression profile and tumorigenic mechanisms of CD97 (ADGRE5) in glioblastoma render it a targetable vulnerability
Glioblastoma (GBM) is the most common and aggressive primary brain malignancy.
Adhesion G protein-coupled receptors (aGPCRs) have attracted interest for their potential as …
Adhesion G protein-coupled receptors (aGPCRs) have attracted interest for their potential as …
Noncoding RNAs in the glycolysis of ovarian cancer
C Zhang, N Liu - Frontiers in Pharmacology, 2022 - frontiersin.org
Energy metabolism reprogramming is the characteristic feature of tumors. The
tumorigenesis, metastasis, and drug resistance of ovarian cancer (OC) is dependent on …
tumorigenesis, metastasis, and drug resistance of ovarian cancer (OC) is dependent on …
The YTHDC1/GLUT3/RNF183 axis forms a positive feedback loop that modulates glucose metabolism and bladder cancer progression
B Yan, X Li, M Peng, Y Zuo, Y Wang, P Liu… - … & Molecular Medicine, 2023 - nature.com
Aberrant glucose metabolism is a characteristic of bladder cancer. Hyperglycemia
contributes to the development and progression of bladder cancer. However, the underlying …
contributes to the development and progression of bladder cancer. However, the underlying …