Pathophysiology, phenotypes and management of type 2 diabetes mellitus in Indian and Chinese populations

C Ke, KMV Narayan, JCN Chan, P Jha… - Nature Reviews …, 2022 - nature.com
Nearly half of all adults with type 2 diabetes mellitus (T2DM) live in India and China. These
populations have an underlying predisposition to deficient insulin secretion, which has a key …

Atherosclerotic cardiovascular disease in South Asians in the United States: epidemiology, risk factors, and treatments: a scientific statement from the American Heart …

AS Volgman, LS Palaniappan, NT Aggarwal, M Gupta… - Circulation, 2018 - Am Heart Assoc
South Asians (from Bangladesh, Bhutan, India, the Maldives, Nepal, Pakistan, and Sri
Lanka) make up one quarter of the world's population and are one of the fastest-growing …

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

R Malik, G Chauhan, M Traylor, M Sargurupremraj… - Nature …, 2018 - nature.com
Stroke has multiple etiologies, but the underlying genes and pathways are largely unknown.
We conducted a multiancestry genome-wide-association meta-analysis in 521,612 …

Type 2 diabetes: demystifying the global epidemic

R Unnikrishnan, R Pradeepa, SR Joshi, V Mohan - Diabetes, 2017 - Am Diabetes Assoc
Type 2 diabetes (T2D) has attained the status of a global pandemic, spreading from affluent
industrialized nations to the emerging economies of Asia, Latin America, and Africa. There is …

Biological roles of glycans

A Varki - Glycobiology, 2017 - academic.oup.com
Simple and complex carbohydrates (glycans) have long been known to play major
metabolic, structural and physical roles in biological systems. Targeted microbial binding to …

[HTML][HTML] Diabetes mellitus and its complications in India

R Unnikrishnan, RM Anjana, V Mohan - Nature Reviews Endocrinology, 2016 - nature.com
India is one of the epicentres of the global diabetes mellitus pandemic. Rapid
socioeconomic development and demographic changes, along with increased susceptibility …

Genetics of type 2 diabetes—pitfalls and possibilities

RB Prasad, L Groop - Genes, 2015 - mdpi.com
Type 2 diabetes (T2D) is a complex disease that is caused by a complex interplay between
genetic, epigenetic and environmental factors. While the major environmental factors, diet …

Genetic susceptibility to type 2 diabetes and obesity: from genome-wide association studies to rare variants and beyond

N Grarup, CH Sandholt, T Hansen, O Pedersen - Diabetologia, 2014 - Springer
During the past 7 years, genome-wide association studies have shed light on the
contribution of common genomic variants to the genetic architecture of type 2 diabetes …

Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes

M Imamura, A Takahashi, T Yamauchi, K Hara… - Nature …, 2016 - nature.com
Genome-wide association studies (GWAS) have identified more than 80 susceptibility loci
for type 2 diabetes (T2D), but most of its heritability still remains to be elucidated. In this …

[LIBRO][B] Holy science: The biopolitics of Hindu nationalism

B Subramaniam - 2019 - books.google.com
Behind the euphoric narrative of India as an emerging world power lies a complex and
evolving relationship between science and religion. Evoking the rich mythology of …