Cell segmentation in imaging-based spatial transcriptomics

V Petukhov, RJ Xu, RA Soldatov, P Cadinu… - Nature …, 2022 - nature.com
Single-molecule spatial transcriptomics protocols based on in situ sequencing or
multiplexed RNA fluorescent hybridization can reveal detailed tissue organization. However …

Novel insights into Hodgkin lymphoma biology by single-cell analysis

T Aoki, C Steidl - Blood, 2023 - ashpublications.org
The emergence and rapid development of single-cell technologies mark a paradigm shift in
cancer research. Various technology implementations represent powerful tools to …

Seens: Nuclei segmentation in pap smear images with selective edge enhancement

M Zhao, H Wang, Y Han, X Wang, HN Dai… - Future Generation …, 2021 - Elsevier
Accurate nuclei segmentation, as an indispensable basis and core link for multi-cell cervical
image analysis, plays an important role in automatic pre-cancer detection. However, poor …

Neuroblastoma cells classification through learning approaches by direct analysis of digital holograms

MD Priscoli, P Memmolo, G Ciaparrone… - IEEE Journal of …, 2021 - ieeexplore.ieee.org
The label-free single cell analysis by machine and Deep Learning, in combination with
digital holography in transmission microscope configuration, is becoming a powerful …

A Systematic Survey on Biological Cell Image Segmentation and Cell Counting Techniques in Microscopic Images Using Machine Learning

H Singh, H Kaur - Wireless Personal Communications, 2024 - Springer
The article focuses on the concepts of Cell Image Segmentation (CIS) and the gradual
introduction of cell counting. Motivated by the rapid development of Machine learning (ML) …

[HTML][HTML] Automated Seedling Contour Determination and Segmentation Using Support Vector Machine and Image Features

Samsuzzaman, MN Reza, S Islam, KH Lee, MA Haque… - Agronomy, 2024 - mdpi.com
Boundary contour determination during seedling image segmentation is critical for accurate
object detection and morphological characterization in agricultural machine vision systems …

A two-stage approach solo_GAN for overlap** cervical cell segmentation based on single-cell identification and boundary generation

Z He, D Jia, C Zhang, Z Li, N Wu - Applied Intelligence, 2024 - Springer
Accurate cell segmentation is a pivotal step throughout the cervical cancer treatment
continuum, encompassing early screening, guiding treatment decisions, and assessing long …

An approach of separating the overlapped cells or nuclei based on the outer Canny edges and morphological erosion

W Zhang, Z Wang - Cytometry Part A, 2024 - Wiley Online Library
In biomedicine, the automatic processing of medical microscope images plays a key role in
the subsequent analysis and diagnosis. Cell or nucleus segmentation is one of the most …

Bayesian segmentation of spatially resolved transcriptomics data

V Petukhov, RA Soldatov, K Khodosevich… - bioRxiv, 2020 - biorxiv.org
Spatial transcriptomics is an emerging stack of technologies, which adds spatial dimension
to conventional single-cell RNA-sequencing. New protocols, based on in situ sequencing or …