Current challenges and opportunities in treating glioblastoma
Glioblastoma multiforme (GBM), the most common and aggressive primary brain tumor, has
a high mortality rate despite extensive efforts to develop new treatments. GBM exhibits both …
a high mortality rate despite extensive efforts to develop new treatments. GBM exhibits both …
Oncogenes and tumor suppressor genes in breast cancer: potential diagnostic and therapeutic applications
C Osborne, P Wilson, D Tripathy - The oncologist, 2004 - academic.oup.com
Abstract Learning Objectives After completing this course, the reader will be able to:
Differentiate between the actions of oncogenes and tumor suppressor genes in the …
Differentiate between the actions of oncogenes and tumor suppressor genes in the …
Identification of proteins in human cytomegalovirus (HCMV) particles: the HCMV proteome
SM Varnum, DN Streblow, ME Monroe, P Smith… - Journal of …, 2004 - Am Soc Microbiol
Human cytomegalovirus (HCMV), a member of the herpesvirus family, is a large complex
enveloped virus composed of both viral and cellular gene products. While the sequence of …
enveloped virus composed of both viral and cellular gene products. While the sequence of …
[BOOK][B] Qualitative health research: Creating a new discipline
JM Morse - 2016 - taylorfrancis.com
The leading figure in qualitative health research (QHR), Janice M. Morse, asserts that QHR
is its own separate discipline—distinct from both traditional health research and other kinds …
is its own separate discipline—distinct from both traditional health research and other kinds …
[HTML][HTML] Cellular interactions in the tumor microenvironment: the role of secretome
BR da Cunha, C Domingos, ACB Stefanini… - Journal of …, 2019 - ncbi.nlm.nih.gov
Over the past years, it has become evident that cancer initiation and progression depends
on several components of the tumor microenvironment, including inflammatory and immune …
on several components of the tumor microenvironment, including inflammatory and immune …
[HTML][HTML] Advances and challenges in liquid chromatography-mass spectrometry-based proteomics profiling for clinical applications
Recent advances in proteomics technologies provide tremendous opportunities for
biomarker-related clinical applications; however, the distinctive characteristics of human …
biomarker-related clinical applications; however, the distinctive characteristics of human …
Proteomic characterization of the interstitial fluid perfusing the breast tumor microenvironment: a novel resource for biomarker and therapeutic target discovery
Clinical cancer proteomics aims at the identification of markers for early detection and
predictive purposes, as well as to provide novel targets for drug discovery and therapeutic …
predictive purposes, as well as to provide novel targets for drug discovery and therapeutic …
Secreted proteins as a fundamental source for biomarker discovery
M Stastna, JE Van Eyk - Proteomics, 2012 - Wiley Online Library
The proteins secreted by various cells (the secretomes) are a potential rich source of
biomarkers as they reflect various states of the cells at real time and at given conditions. To …
biomarkers as they reflect various states of the cells at real time and at given conditions. To …
The cancer cell secretome: a good source for discovering biomarkers?
Cancer is a leading cause of death. Early detection is usually associated with better clinical
outcomes. Recent advances in genomics and proteomics raised hopes that new biomarkers …
outcomes. Recent advances in genomics and proteomics raised hopes that new biomarkers …
Macrophage responses to silica nanoparticles are highly conserved across particle sizes
KM Waters, LM Masiello, RC Zangar… - Toxicological …, 2009 - academic.oup.com
Concerns about the potential adverse health effects of engineered nanoparticles stems in
part from the possibility that some materials display unique chemical and physical properties …
part from the possibility that some materials display unique chemical and physical properties …