Acute leukemias (both myeloid and lymphoblastic) are a group of diseases for which each
year more successful therapies are implemented. However, in a subset of cases the overall …

Abstract Purpose of Review Recent treatment advances in both acute myeloid leukemia and
acute lymphoblastic leukemia have drastically improved outcomes for these diseases, but …

Neural cell adhesion molecule 1 (NCAM1; CD56) is expressed in up to 20% of acute
myeloid leukemia (AML) patients. NCAM1 is widely used as a marker of minimal residual …

3 Ivanova NB, Dimos JT, Schaniel C, Hackney JA, Moore KA, Lemischka IR. A stem cell
molecular signature. Science 2002; 298: 601-604. 4 Wang J, Sun Q, Morita Y, Jiang H …

Acute myeloid leukemia (AML) is the most common form of acute leukemia diagnosed in
adults. Despite advances in medical care, the treatment of AML still faces many challenges …

Simple Summary Childhood acute myeloid leukemia (AML) remains a cancer with poor
overall outcomes. Myeloid sarcomas (MS) are extramedullary masses of leukemia cells that …

The role of the vascular microenvironment is increasingly studied in acute myeloid
leukaemia (AML). Complex interactions between endothelial cells (ECs) and pre-leukaemic …

The blue whale, Balaenoptera musculus, is the largest animal known to have ever existed,
making it an important case study in longevity and resistance to cancer. To further this and …

Philadelphia-negative myeloproliferative neoplasms (MPN) are clonal hematological
diseases associated with driver mutations in JAK2, CALR, and MPL genes. Moreover …

Acute myeloid leukemia (AML) is a diverse malignancy originating from myeloid progenitor
cells, with significant genetic and clinical variability. Modern classification systems like those …