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[HTML][HTML] Epigenetic modulations in triple-negative breast cancer: Therapeutic implications for tumor microenvironment
L Zhou, CW Yu - Pharmacological research, 2024 - Elsevier
Triple-negative breast cancer (TNBC) is an aggressive subtype lacking estrogen receptors,
progesterone receptors and lacks HER2 overexpression. This absence of critical molecular …
progesterone receptors and lacks HER2 overexpression. This absence of critical molecular …
Advances in targeted therapy of breast cancer with antibody-drug conjugate
Antibody–drug conjugates (ADCs) are a potential and promising therapy for a wide variety of
cancers, including breast cancer. ADC-based drugs represent a rapidly growing field of …
cancers, including breast cancer. ADC-based drugs represent a rapidly growing field of …
Natural compounds, optimal combination of brusatol and polydatin promote anti-tumor effect in breast cancer by targeting Nrf2 signaling pathway
Triple-negative breast cancer (TNBC) has been clearly recognized as a heterogeneous
tumor with the worst prognosis among the subtypes of breast cancer (BC). The advent and …
tumor with the worst prognosis among the subtypes of breast cancer (BC). The advent and …
Disclosing a metabolic signature of cisplatin resistance in MDA-MB-231 triple-negative breast cancer cells by NMR metabolomics
TJ Carneiro, ALMB Carvalho, M Vojtek, IF Carmo… - Cancer Cell …, 2023 - Springer
This work compared the metabolic profile of a parental MDA-MB-231 cisplatin-sensitive
triple negative breast cancer (TNBC) cell line with that of a derived cisplatin-resistant line, to …
triple negative breast cancer (TNBC) cell line with that of a derived cisplatin-resistant line, to …
Repurposing proteasome inhibitors for improved treatment of triple-negative breast cancer
Triple-negative breast cancer (TNBC) is associated with poor prognosis and limited
treatment options due to the lack of important receptors (estrogen receptor [ER] …
treatment options due to the lack of important receptors (estrogen receptor [ER] …
[HTML][HTML] Polydatin: A natural compound with multifaceted anticancer properties
Cancer poses a significant global health challenge, contributing to substantial mortality rates
and driving the urgent need for exploration into bioactive compounds with potent anticancer …
and driving the urgent need for exploration into bioactive compounds with potent anticancer …
Sacituzumab govitecan and radiotherapy in metastatic, triple-negative, and BRCA-mutant breast cancer patient with active brain metastases: a case report
P di Mauro, G Schivardi, R Pedersini, L Laini… - Frontiers in …, 2023 - frontiersin.org
Background Triple-negative breast cancer (TNBC) is an aggressive cancer subtype, owing
to its high metastatic potential: Patients who develop brain metastases (BMs) have a poor …
to its high metastatic potential: Patients who develop brain metastases (BMs) have a poor …
New biomarkers and treatment advances in triple-negative breast cancer
Triple-negative breast cancer (TNBC) is a specific subtype of breast cancer lacking hormone
receptor expression and HER2 gene amplification. TNBC represents a heterogeneous …
receptor expression and HER2 gene amplification. TNBC represents a heterogeneous …
Combination of ionizing radiation and 2-thio-6-azauridine induces cell death in radioresistant triple negative breast cancer cells by downregulating CD151 expression
Background Triple-negative breast cancer (TNBC) represents the most aggressive subtype
of breast cancer and is frequently resistant to therapy, ultimately resulting in treatment …
of breast cancer and is frequently resistant to therapy, ultimately resulting in treatment …
Towards agility in breast cancer treatment principles as adopted from agile software engineering
Purpose The complex nature of breast cancer demands flexible and adaptable principles
that can account for the diverse characteristics and evolving conditions of each patient …
that can account for the diverse characteristics and evolving conditions of each patient …