MicroRNAs (miRNAs) are very powerful genetic regulators, as evidenced by the fact that a
single miRNA can direct entire cellular pathways via interacting with a broad spectrum of …

The aged adaptive immune system is characterized by progressive dysfunction as well as
increased autoimmunity. This decline is responsible for elevated susceptibility to infection …

Tumor immunotherapy is a promising therapeutic strategy for patients with advanced
cancers. T cells are key mediators of antitumor function that specifically recognize and react …

During chronic infection and cancer, a self-renewing CD8+ T cell subset maintains long-term
immunity and is critical to the effectiveness of immunotherapy. These stem-like CD8+ T cells …

Abstract High oxidative stress, Th1/Th17 immune response, M1 macrophage inflammation,
and cell death are associated with cardiovascular diseases. Controlled oxidative stress …

Regular physical exercise has been recognized as a potent modulator of immune function,
with its effects including enhanced immune surveillance, reduced inflammation, and …

MicroRNAs (miRNAs) are evolutionally conserved, single-stranded RNAs that regulate gene
expression at the posttranscriptional level by disrupting translation. MiRNAs are key players …

Considerable attention has been directed towards exploring the potential efficacy of miR-
155 in the realm of cancer immunotherapy. Elevated levels of miR-155 in dendritic cells …

Substantial evolution in cancer therapy has been witnessed lately, steering mainly towards
immunotherapeutic approaches, replacing or in combination with classical therapies …

Purpose MiR-155 is a member of the microRNAs (miRNAs) family and regulates gene
expression post-transcriptionally by binding to the 3'UTR of target mRNA. MiR-155 has a …