Cerebral cortical structural alteration patterns across four major psychiatric disorders in 5549 individuals
According to the operational diagnostic criteria, psychiatric disorders such as schizophrenia
(SZ), bipolar disorder (BD), major depressive disorder (MDD), and autism spectrum disorder …
(SZ), bipolar disorder (BD), major depressive disorder (MDD), and autism spectrum disorder …
Advances in the knowledge and therapeutics of schizophrenia, major depression disorder, and bipolar disorder from human brain organoid research
R Villanueva - Frontiers in Psychiatry, 2023 - frontiersin.org
Tridimensional cultures of human induced pluripotent cells (iPSCs) experimentally directed
to neural differentiation, termed “brain organoids” are now employed as an in vitro assay that …
to neural differentiation, termed “brain organoids” are now employed as an in vitro assay that …
[HTML][HTML] Convergence of brain transcriptomic and neuroimaging patterns in schizophrenia, bipolar disorder, autism spectrum disorder, and major depressive disorder
Background Psychiatric conditions show overlap in their symptoms, genetics, and
involvement in brain areas and circuits. Structural alterations in the brain have been found to …
involvement in brain areas and circuits. Structural alterations in the brain have been found to …
Advanced nano engineering of surface-enhanced Raman scattering technologies for sensing applications
Surface-enhanced Raman scattering has attracted a lot of attention as a very effective
analytical method in the field of biosensors. The method makes use of the enhanced signal …
analytical method in the field of biosensors. The method makes use of the enhanced signal …
A phylogenetically-conserved axis of thalamocortical connectivity in the human brain
The thalamus enables key sensory, motor, emotive, and cognitive processes via
connections to the cortex. These projection patterns are traditionally considered to originate …
connections to the cortex. These projection patterns are traditionally considered to originate …
Connectome architecture shapes large-scale cortical alterations in schizophrenia: a worldwide ENIGMA study
Schizophrenia is a prototypical network disorder with widespread brain-morphological
alterations, yet it remains unclear whether these distributed alterations robustly reflect the …
alterations, yet it remains unclear whether these distributed alterations robustly reflect the …
[HTML][HTML] Neuroimaging and biosample collection in the Toronto Adolescent and Youth Cohort Study: Rationale, methods, and early data
Abstract Background The Toronto Adolescent and Youth (TAY) Cohort Study will
characterize the neurobiological trajectories of psychosis spectrum symptoms, functioning …
characterize the neurobiological trajectories of psychosis spectrum symptoms, functioning …
Proof-of-concept recall-by-genotype study of extremely low and high Alzheimer's polygenic risk reveals autobiographical deficits and cingulate cortex correlates
Background Genome-wide association studies demonstrate that Alzheimer's disease (AD)
has a highly polygenic architecture, where thousands of independent genetic variants …
has a highly polygenic architecture, where thousands of independent genetic variants …
Multimodal map** of regional brain vulnerability to focal cortical dysplasia
Focal cortical dysplasia (FCD) type II is a highly epileptogenic developmental malformation
and a common cause of surgically treated drug-resistant epilepsy. While clinical …
and a common cause of surgically treated drug-resistant epilepsy. While clinical …
Abnormal structural‒functional coupling patterning in progressive supranuclear palsy is associated with diverse gradients and histological features
J Qu, R Zhu, Y Wu, G Xu, D Wang - Communications Biology, 2024 - nature.com
The anatomy of the brain supports inherent processes, fostering mental abilities and
eventually facilitating adaptive behavior. Recent studies have shown that progressive …
eventually facilitating adaptive behavior. Recent studies have shown that progressive …