Post-traumatic stress disorder: clinical and translational neuroscience from cells to circuits

KJ Ressler, S Berretta, VY Bolshakov… - Nature Reviews …, 2022 - nature.com
Post-traumatic stress disorder (PTSD) is a maladaptive and debilitating psychiatric disorder,
characterized by re-experiencing, avoidance, negative emotions and thoughts, and …

[HTML][HTML] Methodological and quality flaws in the use of artificial intelligence in mental health research: systematic review

R Tornero-Costa, A Martinez-Millana… - JMIR Mental …, 2023 - mental.jmir.org
Background: Artificial intelligence (AI) is giving rise to a revolution in medicine and health
care. Mental health conditions are highly prevalent in many countries, and the COVID-19 …

A validated predictive algorithm of post-traumatic stress course following emergency department admission after a traumatic stressor

K Schultebraucks, AY Shalev, V Michopoulos… - Nature medicine, 2020 - nature.com
Annually, approximately 30 million patients are discharged from the emergency department
(ED) after a traumatic event. These patients are at substantial psychiatric risk, with …

To predict, prevent, and manage post-traumatic stress disorder (PTSD): a review of pathophysiology, treatment, and biomarkers

GI Al Jowf, ZT Ahmed, RA Reijnders, L de Nijs… - International journal of …, 2023 - mdpi.com
Post-traumatic stress disorder (PTSD) can become a chronic and severely disabling
condition resulting in a reduced quality of life and increased economic burden. The disorder …

Structural inequities contribute to racial/ethnic differences in neurophysiological tone, but not threat reactivity, after trauma exposure

NG Harnett, N Fani, S Carter, LD Sanchez… - Molecular …, 2023 - nature.com
Considerable racial/ethnic disparities persist in exposure to life stressors and
socioeconomic resources that can directly affect threat neurocircuitry, particularly the …

Multimodal categorical and dimensional approaches to understanding threat conditioning and its extinction in individuals with anxiety disorders

MF Marin, MZ Hammoud, H Klumpp, NM Simon… - JAMA …, 2020 - jamanetwork.com
Importance The Research Domain Criteria project of the National Institute of Mental Health
aims to guide neuropsychiatry toward precision medicine. Its inception was partly in …

Emotion dysregulation is associated with increased prospective risk for chronic PTSD development

I Pencea, AP Munoz, JL Maples-Keller, D Fiorillo… - Journal of psychiatric …, 2020 - Elsevier
While emotion dysregulation is associated with many psychological disorders, including
posttraumatic stress disorder (PTSD), it remains uncertain whether pre-existing emotion …

Preclinical models of chronic stress: adaptation or pathology?

JJ Radley, JP Herman - Biological Psychiatry, 2023 - Elsevier
The experience of prolonged stress changes how individuals interact with their environment
and process interoceptive cues, with the end goal of optimizing survival and well-being in …

[HTML][HTML] The influence of sleep on fear extinction in trauma-related disorders

EF Pace-Schott, J Seo, R Bottary - Neurobiology of stress, 2023 - Elsevier
Abstract In Posttraumatic Stress Disorder (PTSD), fear and anxiety become dysregulated
following psychologically traumatic events. Regulation of fear and anxiety involves both high …

[HTML][HTML] Resilience or susceptibility to traumatic stress: potential influence of the microbiome

A Tanelian, B Nankova, M Miari, RJ Nahvi… - Neurobiology of …, 2022 - Elsevier
Exposure to traumatic stress is a major risk factor for development of neuropsychiatric
disorders in a sub-population of individuals, while others remain resilient. The mechanisms …