Adhesion receptors of the immune system

TA Springer - Nature, 1990 - nature.com
The adhesive interactions of cells with other cells and with the extracellular matrix are crucial
to all developmental processes, but have a central role in the functions of the immune …

Platelet integrin αIIbβ3: signal transduction, regulation, and its therapeutic targeting

J Huang, X Li, X Shi, M Zhu, J Wang, S Huang… - Journal of hematology & …, 2019 - Springer
Integrins are a family of transmembrane glycoprotein signaling receptors that can transmit
bioinformation bidirectionally across the plasma membrane. Integrin αIIbβ3 is expressed at a …

New tools for studying microglia in the mouse and human CNS

ML Bennett, FC Bennett, SA Liddelow… - Proceedings of the …, 2016 - National Acad Sciences
The specific function of microglia, the tissue resident macrophages of the brain and spinal
cord, has been difficult to ascertain because of a lack of tools to distinguish microglia from …

α4β7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1

C Berlin, EL Berg, MJ Briskin, DP Andrew, PJ Kilshaw… - Cell, 1993 - cell.com
The mucosal vascular addressin, MAdCAM-1, is an immunoglobulin superfamily adhesion
molecule for lymphocytes that is expressed by mucosal venules and helps direct lymphocyte …

Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies

VM Weaver, OW Petersen, F Wang… - The Journal of cell …, 1997 - rupress.org
In a recently developed human breast cancer model, treatment of tumor cells in a 3-
dimensional culture with inhibitory β1-integrin antibody or its Fab fragments led to a striking …

Form and function: the laminin family of heterotrimers

H Colognato, PD Yurchenco - Developmental dynamics: an …, 2000 - Wiley Online Library
The laminins are a family of glycoproteins that provide an integral part of the structural
scaffolding of basement membranes in almost every animal tissue. Each laminin is a …

Angiogenesis in wound repair: angiogenic growth factors and the extracellular matrix

J Li, YP Zhang, RS Kirsner - Microscopy research and …, 2003 - Wiley Online Library
Angiogenesis is critical to wound repair. Newly formed blood vessels participate in
provisional granulation tissue formation and provide nutrition and oxygen to growing tissues …

Cell adhesion mechanisms in platelets

D Varga-Szabo, I Pleines… - … , thrombosis, and vascular …, 2008 - Am Heart Assoc
At sites of vascular injury, platelets come into contact with the subendothelial extracellular
matrix which triggers their activation and the formation of a hemostatic plug. This process is …

Continuing education course# 2: current understanding of hemostasis

AJ Gale - Toxicologic pathology, 2011 - journals.sagepub.com
The goal of this review is to briefly summarize the two primary pathways of hemostasis,
primary hemostasis and secondary hemostasis, as well as to summarize anticoagulant …

Integrin adhesion molecules in the human endometrium. Correlation with the normal and abnormal menstrual cycle.

BA Lessey, L Damjanovich, C Coutifaris… - The Journal of …, 1992 - Am Soc Clin Investig
Integrins are a class of cell adhesion molecules that participate in cell-cell and cell-
substratum interactions and are present on essentially all human cells. The distribution of …