Mixed-effects models for the design and analysis of stepped wedge cluster randomized trials: an overview

F Li, JP Hughes, K Hemming… - … Methods in Medical …, 2021 - journals.sagepub.com
The stepped wedge cluster randomized design has received increasing attention in
pragmatic clinical trials and implementation science research. The key feature of the design …

Natural language processing in low back pain and spine diseases: a systematic review

L Bacco, F Russo, L Ambrosio, F D'Antoni… - Frontiers in …, 2022 - frontiersin.org
Natural Language Processing (NLP) is a discipline at the intersection between Computer
Science (CS), Artificial Intelligence (AI), and Linguistics that leverages unstructured human …

Predicting decompression surgery by applying multimodal deep learning to patients' structured and unstructured health data

C Jujjavarapu, P Suri, V Pejaver, J Friedly… - BMC Medical Informatics …, 2023 - Springer
Background Low back pain (LBP) is a common condition made up of a variety of anatomic
and clinical subtypes. Lumbar disc herniation (LDH) and lumbar spinal stenosis (LSS) are …

Comparison of natural language processing rules-based and machine-learning systems to identify lumbar spine imaging findings related to low back pain

WK Tan, S Hassanpour, PJ Heagerty, SD Rundell… - Academic radiology, 2018 - Elsevier
Rationale and Objectives To evaluate a natural language processing (NLP) system built with
open-source tools for identification of lumbar spine imaging findings related to low back pain …

Enhancing the use of EHR systems for pragmatic embedded research: lessons from the NIH Health Care Systems Research Collaboratory

RL Richesson, KS Marsolo, BJ Douthit… - Journal of the …, 2021 - academic.oup.com
Objective We identified challenges and solutions to using electronic health record (EHR)
systems for the design and conduct of pragmatic research. Materials and Methods Since …

The effect of including benchmark prevalence data of common imaging findings in spine image reports on health care utilization among adults undergoing spine …

JG Jarvik, EN Meier, KT James, LS Gold… - JAMA network …, 2020 - jamanetwork.com
Importance Lumbar spine imaging frequently reveals findings that may seem alarming but
are likely unrelated to pain. Prior work has suggested that inserting data on the prevalence …

Statistical lessons learned for designing cluster randomized pragmatic clinical trials from the NIH Health Care Systems Collaboratory Biostatistics and Design Core

AJ Cook, E Delong, DM Murray, WM Vollmer… - Clinical …, 2016 - journals.sagepub.com
Background/aims: Pragmatic clinical trials embedded within health care systems provide an
important opportunity to evaluate new interventions and treatments. Networks have recently …

Predictors of lumbar spine degeneration and low back pain in the community: the Johnston County Osteoarthritis Project

AP Goode, RJ Cleveland, SZ George… - Arthritis care & …, 2022 - Wiley Online Library
Objective To determine the incidence and worsening of lumbar spine structure and low back
pain (LBP) and whether they are predicted by demographic characteristics or clinical …

Power and sample size calculation for stepped-wedge designs with discrete outcomes

F **a, JP Hughes, EC Voldal, PJ Heagerty - Trials, 2021 - Springer
Background Stepped-wedge designs (SWD) are increasingly used to evaluate the impact of
changes to the process of care within health care systems. However, to generate definitive …

Using natural language processing of free-text radiology reports to identify type 1 modic endplate changes

HT Huhdanpaa, WK Tan, SD Rundell, P Suri… - Journal of digital …, 2018 - Springer
Electronic medical record (EMR) systems provide easy access to radiology reports and offer
great potential to support quality improvement efforts and clinical research. Harnessing the …