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Small molecule drug metabolite synthesis and identification: why, when and how?
J Shanu-Wilson, S Coe, L Evans, J Steele… - Drug Discovery …, 2024 - Elsevier
The drug discovery and development process encompasses the interrogation of metabolites
arising from the biotransformation of drugs. Here we look at why, when and how metabolites …
arising from the biotransformation of drugs. Here we look at why, when and how metabolites …
A MIST conception: what has been learned from twenty years of human metabolite safety assessment?
D Luffer-Atlas, RS Obach, DA Smith - Medicinal Chemistry Research, 2023 - Springer
In this review, we trace origins of the joint initiative of the pharmaceutical industry and major
regulatory authorities to provide a framework for the identification, quantification, and testing …
regulatory authorities to provide a framework for the identification, quantification, and testing …
Quercetin derivatives as potential inhibitors of Nipah Virus Phosphoprotein through in Silico Drug Design approaches
Abstract The Nipah virus (NiV) is a pathogenic infection presenting a substantial risk to both
human and animal communities. Despite its virulence, there are currently no available drugs …
human and animal communities. Despite its virulence, there are currently no available drugs …
Special Section on Perspectives on Drug Metabolism and Disposition, Part I
Y Lai, X Ding - Drug Metabolism and Disposition, 2023 - dmd.aspetjournals.org
The “Perspectives on Drug Metabolism and Disposition” special section features articles
contributed by the current associate editors of Drug Metabolism and Disposition (DMD) to …
contributed by the current associate editors of Drug Metabolism and Disposition (DMD) to …