Prolonged elevated oxidative stress (OS) possesses negative effect on cell structure and
functioning, and is associated with the development of numerous disorders. Naturally …

Melatonin is a serotonin-derived pineal gland hormone with many biological functions like
regulating the sleep-wake cycle, circadian rhythm, menstrual cycle, aging, immunity, and …

Melatonin is a multifunctional and ubiquitous molecule. In animals, melatonin is a hormone
that is involved in a wide range of physiological activities and is also an excellent …

Ovarian cancer (OC) is the most lethal gynecologic malignancy, and melatonin has shown
various antitumor properties. Herein, we investigated the influence of melatonin therapy on …

Atrazine (ATZ) is a widely used herbicide that has toxic effects on animals. Melatonin (MLT)
is a natural hormone with strong antioxidant properties. However, the effect of MLT on the …

Increasing evidence suggests that tumor development requires not only oncogene/tumor
suppressor mutations to drive the growth, survival, and metastasis but also metabolic …

Introduction Melatonin, originally isolated from the mammalian pineal gland, was
subsequently identified in many animal cell types and in plants. While melatonin was …

Mitochondria are critical for cellular energetic metabolism, intracellular signaling
orchestration and programmed death regulation. Therefore, mitochondrial dysfunction is …

Background Ovarian cancer is a highly aggressive disease that is frequently diagnosed in
advanced stages. Melatonin, with its numerous antitumor properties, holds great promise in …

Ovarian cancer (OC) adjusts energy metabolism in favor of its progression and
dissemination. Because melatonin (Mel) has antitumor actions, we investigated its impact on …