Oxidative stress and inflammation in diabetic nephropathy: role of polyphenols

Q **, T Liu, Y Qiao, D Liu, L Yang, H Mao… - Frontiers in …, 2023 - frontiersin.org
Diabetic nephropathy (DN) often leads to end-stage renal disease. Oxidative stress
demonstrates a crucial act in the onset and progression of DN, which triggers various …

Molecular mechanisms for the vicious cycle between insulin resistance and the inflammatory response in obesity

D Szukiewicz - International Journal of Molecular Sciences, 2023 - mdpi.com
The comprehensive anabolic effects of insulin throughout the body, in addition to the control
of glycemia, include ensuring lipid homeostasis and anti-inflammatory modulation …

[HTML][HTML] Automated diabetic retinopathy detection using horizontal and vertical patch division-based pre-trained DenseNET with digital fundus images

SG Kobat, N Baygin, E Yusufoglu, M Baygin, PD Barua… - Diagnostics, 2022 - mdpi.com
Diabetic retinopathy (DR) is a common complication of diabetes that can lead to progressive
vision loss. Regular surveillance with fundal photography, early diagnosis, and prompt …

[HTML][HTML] Pharmacological and therapeutic applications of esculetin

SS Garg, J Gupta, D Sahu, CJ Liu - International journal of molecular …, 2022 - mdpi.com
Esculetin is a coumarin compound, which belongs to the class of benzopyrone enriched in
various plants such as Sonchus grandifolius, Aesculus turbinata, etc. Free radicals lead to …

[HTML][HTML] Phytochemical profile and antioxidant capacity, α-amylase and α-glucosidase inhibitory activities of Oxalis pes-caprae extracts in alloxan-induced diabetic …

I Kabach, N Bouchmaa, Z Zouaoui, A Ennoury… - Biomedicine & …, 2023 - Elsevier
Diabetes and its complications are closely correlated with chronic hyperglycemia, causing
severe oxidative stress and leading to glycation reaction with formation of advanced …

The impact of aging and oxidative stress in metabolic and nervous system disorders: programmed cell death and molecular signal transduction crosstalk

K Maiese - Frontiers in immunology, 2023 - frontiersin.org
Life expectancy is increasing throughout the world and coincides with a rise in non-
communicable diseases (NCDs), especially for metabolic disease that includes diabetes …

Childhood obesity, metabolic syndrome, and oxidative stress: microRNAs go on stage

Á González-Domínguez, T Belmonte… - Reviews in Endocrine …, 2023 - Springer
The incidence of childhood obesity and metabolic syndrome has grown notably in the last
years, becoming major public health burdens in developed countries. Nowadays, oxidative …

Hypoglycemic activity in vitro and vivo of a water-soluble polysaccharide from Astragalus membranaceus

X Chen, C Chen, X Fu - Food & Function, 2022 - pubs.rsc.org
The polysaccharide AMP as one main bioactive component of Astragalus membranaceus
(Fisch.) Bunge was separated and characterized. The results showed that AMP was a typical …

A review of medicinal plants with renoprotective activity in diabetic nephropathy animal models

IMWA Putra, N Fakhrudin, A Nurrochmad, S Wahyuono - Life, 2023 - mdpi.com
Diabetic nephropathy (DN), also recognized as diabetic kidney disease, is a kidney
malfunction caused by diabetes mellitus. A possible contributing factor to the onset of DN is …

[HTML][HTML] Protective role of mitochondrial uncoupling proteins against age-related oxidative stress in type 2 diabetes mellitus

M Čater, LK Bombek - Antioxidants, 2022 - mdpi.com
The accumulation of oxidative damage to DNA and other biomolecules plays an important
role in the etiology of aging and age-related diseases such as type 2 diabetes mellitus …