This review focuses on the paracrine and endocrine actions of interferon tau (IFNT) during
pregnancy recognition and establishment in ruminants. Pregnancy recognition involves the …

The dialogue between trophectoderm cells of the conceptus and epithelial cells of the
endometrium is critical to CL maintenance and embryo survival. The signal transduction …

Progesterone suppresses uterine immune defenses and predisposes postpartum animals to
nonspecific uterine infections. Progesterone can also suppress uterine eicosanoid …

Postpartum uterine infections reduce reproductive efficiency and have significant animal
welfare and economic consequences. Postpartum uterine infections are classified as …

This article reviews the function of cytokines during early pregnancy of mammals including
the human species. Investigations concerning conceptus and other secretory proteins, their …

Luteal regression is caused by a pulsatile release of prostaglandin (PG) F2α from the uterus
in the late luteal phase in most mammals including cattle. Although it has been proposed in …

Aberrant gene expression in the uterine endometrium and embryo has been the major
causes of pregnancy failure in cattle. However, selecting cows having adequate endometrial …

Embryonic mortality in cattle may occur because of inadequate inhibition of uterine secretion
of prostaglandin (PG) F2α mediated by bovine interferon-τ (bIFN-τ). The objectives of the …

Problem A type I interferon (IFN), termed IFN‐tau (τ), is responsible for the establishment
and maintenance of early pregnancy in cattle and sheep. The control of IFNτ gene (IFNT) …

Trophoblastic bovine interferon-tau (bIFN-τ) suppresses luteolytic pulses of endometrial
prostaglandin F2α (PGF2α) at the time of maternal recognition of pregnancy. This results in …