Advanced targeted therapies in cancer: Drug nanocarriers, the future of chemotherapy

E Pérez-Herrero, A Fernández-Medarde - European journal of …, 2015‏ - Elsevier
Cancer is the second worldwide cause of death, exceeded only by cardiovascular diseases.
It is characterized by uncontrolled cell proliferation and an absence of cell death that, except …

Functionalizing PLGA and PLGA derivatives for drug delivery and tissue regeneration applications

C Martins, F Sousa, F Araújo… - Advanced Healthcare …, 2018‏ - Wiley Online Library
Abstract Poly (lactic‐co‐glycolic) acid (PLGA) is one of the most versatile biomedical
polymers, already approved by regulatory authorities to be used in human research and …

Milk-derived exosomes for oral delivery of paclitaxel

AK Agrawal, F Aqil, J Jeyabalan, WA Spencer… - … , Biology and Medicine, 2017‏ - Elsevier
In this report milk-derived exosomes have been investigated for oral delivery of the
chemotherapeutic drug paclitaxel (PAC) as an alternative to conventional iv therapy for …

PLGA nanoparticles containing various anticancer agents and tumour delivery by EPR effect

S Acharya, SK Sahoo - Advanced drug delivery reviews, 2011‏ - Elsevier
As mortality due to cancer continues to rise, advances in nanotechnology have significantly
become an effective approach for achieving efficient drug targeting to tumour tissues by …

Oral delivery of anticancer drugs: challenges and opportunities

K Thanki, RP Gangwal, AT Sangamwar… - Journal of controlled …, 2013‏ - Elsevier
The present report focuses on the various aspects of oral delivery of anticancer drugs. The
significance of oral delivery in cancer therapeutics has been highlighted which principally …

Herbal nanomedicines: Recent advancements, challenges, opportunities and regulatory overview

PK Teja, J Mithiya, AS Kate, K Bairwa, SK Chauthe - Phytomedicine, 2022‏ - Elsevier
Abstract Background Herbal Nano Medicines (HNMs) are nano-sized medicine containing
herbal drugs as extracts, enriched fractions or biomarker constituents. HNMs have certain …

Polylactide-co-glycolide nanoparticles for controlled delivery of anticancer agents

R Dinarvand, nima Sepehri… - International journal …, 2011‏ - Taylor & Francis
The effectiveness of anticancer agents may be hindered by low solubility in water, poor
permeability, and high efflux from cells. Nanomaterials have been used to enable drug …

Paclitaxel nano-delivery systems: a comprehensive review

P Ma, RJ Mumper - Journal of nanomedicine & …, 2013‏ - pmc.ncbi.nlm.nih.gov
Paclitaxel is one of the most effective chemotherapeutic drugs ever developed and is active
against a broad range of cancers, such as lung, ovarian, and breast cancers. Due to its low …

Theranostic applications of nanomaterials in cancer: drug delivery, image-guided therapy, and multifunctional platforms

A Fernandez-Fernandez, R Manchanda… - Applied biochemistry …, 2011‏ - Springer
Successful cancer management depends on accurate diagnostics along with specific
treatment protocols. Current diagnostic techniques need to be improved to provide earlier …

Size and surface charge of gold nanoparticles determine absorption across intestinal barriers and accumulation in secondary target organs after oral administration

C Schleh, M Semmler-Behnke, J Lipka, A Wenk… - …, 2012‏ - Taylor & Francis
It is of urgent need to identify the exact physico-chemical characteristics which allow
maximum uptake and accumulation in secondary target organs of nanoparticulate drug …