Neuroblastoma: biological insights into a clinical enigma

GM Brodeur - Nature reviews cancer, 2003 - nature.com
Neuroblastoma is a tumour derived from primitive cells of the sympathetic nervous system
and is the most common solid tumour in childhood. Interestingly, most infants experience …

Molecular targeting therapies for neuroblastoma: Progress and challenges

A Zafar, W Wang, G Liu, X Wang, W ** the in vivo fitness landscape of lung adenocarcinoma tumor suppression in mice
ZN Rogers, CD McFarland, IP Winters, JA Seoane… - Nature …, 2018 - nature.com
The functional impact of most genomic alterations found in cancer, alone or in combination,
remains largely unknown. Here we integrate tumor barcoding, CRISPR/Cas9-mediated …

The connections between neural crest development and neuroblastoma

M Jiang, J Stanke, JM Lahti - Current topics in developmental biology, 2011 - Elsevier
Neuroblastoma (NB), the most common extracranial solid tumor in childhood, is an
extremely heterogeneous disease both biologically and clinically. Although significant …

Clonal evolution during metastatic spread in high-risk neuroblastoma

G Gundem, MF Levine, SS Roberts, IY Cheung… - Nature …, 2023 - nature.com
Patients with high-risk neuroblastoma generally present with widely metastatic disease and
often relapse despite intensive therapy. As most studies to date focused on diagnosis …