Advances in ophthalmic drug delivery
Various strategies for ocular drug delivery are considered; from basic formulation techniques
for improving availability of drugs; viscosity enhancers and mucoadhesives aid drug …
for improving availability of drugs; viscosity enhancers and mucoadhesives aid drug …
A biomimetic redox flow battery based on flavin mononucleotide
The versatility in design of redox flow batteries makes them apt to efficiently store energy in
large-scale applications at low cost. The discovery of inexpensive organic electroactive …
large-scale applications at low cost. The discovery of inexpensive organic electroactive …
Functions of hydrotropes in solutions
CV Subbarao, IPK Chakravarthy… - Chemical …, 2012 - Wiley Online Library
Hydrotropes affect a several‐fold increase of the solubility of sparingly soluble solutes under
normal conditions. Their water‐solubility can significantly enhance the solubility of organic …
normal conditions. Their water‐solubility can significantly enhance the solubility of organic …
Hydrotropic solubilization of poorly water-soluble drugs
JY Kim, S Kim, M Papp, K Park, R Pinal - Journal of pharmaceutical …, 2010 - Elsevier
The solubilizing ability of two aromatic hydrotropes, N, N-diethylnicotinamide (DENA) and N,
N-dimethylbenzamide (DMBA), was investigated using a set of 13 poorly soluble, structurally …
N-dimethylbenzamide (DMBA), was investigated using a set of 13 poorly soluble, structurally …
Role of hydrotropes in sparingly soluble drug solubilization: insight from a molecular dynamics simulation and experimental perspectives
Drug molecules' therapeutic efficacy depends on their bioavailability and solubility. But more
than 70% of the formulated drug molecules show limited effectiveness due to low water …
than 70% of the formulated drug molecules show limited effectiveness due to low water …
Cholinium-based ionic liquids as bioinspired hydrotropes to tackle solubility challenges in drug formulation
Hydrotropy is a well-established strategy to enhance the aqueous solubility of hydrophobic
drugs, facilitating their formulation for oral and dermal delivery. However, most hydrotropes …
drugs, facilitating their formulation for oral and dermal delivery. However, most hydrotropes …
An organic bifunctional redox active material for symmetric aqueous redox flow battery
Symmetric redox flow batteries utilizing a single redox active material as catholyte and
anolyte, offer a plausible and unique strategy to alleviate cross-contamination issues during …
anolyte, offer a plausible and unique strategy to alleviate cross-contamination issues during …
A highly reversible anthraquinone-based anolyte for alkaline aqueous redox flow batteries
The development of electroactive organic materials for use in aqueous redox flow battery
(RFB) electrolytes is highly attractive because of their structural flexibility, low cost and …
(RFB) electrolytes is highly attractive because of their structural flexibility, low cost and …
[HTML][HTML] Directly compressed rosuvastatin calcium tablets that offer hydrotropic and micellar solubilization for improved dissolution rate and extent of drug release
The objective was to use caffeine and Soluplus® to improve the dissolution rate and to
maintain a concentration of BCS Class II rosuvastatin calcium that exceeds its solubility …
maintain a concentration of BCS Class II rosuvastatin calcium that exceeds its solubility …
Improving dissolution rate of carbamazepine-glutaric acid cocrystal through solubilization by excess coformer
Purpose The use of soluble cocrystals is a promising strategy for delivering poorly soluble
drugs. However, precipitation of poorly soluble crystal form during dissolution hinders the …
drugs. However, precipitation of poorly soluble crystal form during dissolution hinders the …