Preparation and Post-Assembly Modification of Metallosupramolecular Assemblies from Poly(N-Heterocyclic Carbene) Ligands

MM Gan, JQ Liu, L Zhang, YY Wang, FE Hahn… - Chemical …, 2018 - ACS Publications
Although the coordination chemistry of N-heterocyclic carbenes (NHCs) with transition
metals has been explored for half a century, only in the past ten years has the chemistry of …

Update on metal N-heterocyclic carbene complexes as potential anti-tumor metallodrugs

W Liu, R Gust - Coordination Chemistry Reviews, 2016 - Elsevier
The clinical success of platinum-based chemotherapeutic agents was of enormous impact
on the discovery of novel metal N-heterocyclic carbene (NHC) complexes as potential anti …

Therapeutic evolution of benzimidazole derivatives in the last quinquennial period

W Akhtar, MF Khan, G Verma… - European journal of …, 2017 - Elsevier
Benzimidazole, a fused heterocycle bearing benzene and imidazole has gained
considerable attention in the field of contemporary medicinal chemistry. The moiety is of …

Comprehensive insights into medicinal research on imidazole-based supramolecular complexes

SR Li, YM Tan, L Zhang, CH Zhou - Pharmaceutics, 2023 - mdpi.com
The electron-rich five-membered aromatic aza-heterocyclic imidazole, which contains two
nitrogen atoms, is an important functional fragment widely present in a large number of …

Recent developments in the medicinal applications of silver-NHC complexes and imidazolium salts

NA Johnson, MR Southerland, WJ Youngs - Molecules, 2017 - mdpi.com
Because of their great structural diversity and multitude of chemical properties, N-
heterocyclic carbenes (NHCs) have been utilized in a variety of capacities. Most recently …

Synthesis, characterization and bioactivities of dative donor ligand N-heterocyclic carbene (NHC) precursors and their Ag (I) NHC coordination compounds

A Kazancı, Y Gök, R Kaya, A Aktaş, P Taslimi, İ Gülçin - Polyhedron, 2021 - Elsevier
This study contains the synthesis of N-phthalimidomethyl-substituted NHC precursors and
their Ag (I) NHC coordination compounds. The NHC precursors were synthesized from the 1 …

Recent developments of metal N-heterocyclic carbenes as anticancer agents

SB Aher, PN Muskawar, K Thenmozhi… - European Journal of …, 2014 - Elsevier
Metal based anticancer drugs have demonstrated their crucial role in preventing all types of
cancers whereas their effectiveness is selective with respect to the cancer cells rather than …

Synthesis, Structure, and Anticancer Activity of Symmetrical and Non-symmetrical Silver(I)-N-Heterocyclic Carbene Complexes

M Atif, HN Bhatti, RA Haque, MA Iqbal… - Applied Biochemistry …, 2020 - Springer
Synthesis and anticancer studies of three symmetrically and non-symmetrically substituted
silver (I)-N-Heterocyclic carbene complexes of type [(NHC) 2-Ag] PF 6 (7–9) and their …

Biologically Relevant Silver (I)–N‐Heterocyclic Carbene Complexes: Synthesis, Structure, Intramolecular Interactions, and Applications

S Budagumpi, RA Haque, S Endud… - European Journal of …, 2013 - Wiley Online Library
N‐Heterocyclic carbenes (NHCs) complexed with silver represent new, broad‐spectrum
antimicrobial and anticancer agents, normally with low toxicity profiles, and they provide a …

Molecular docking and in vitro anticancer studies of silver (I)-N-heterocyclic carbene complexes

M Akkoç, S Khan, H Yüce, NB Türkmen, Ş Yaşar… - Heliyon, 2022 - cell.com
A series of symmetric and unsymmetrical benzimidazolium-based N-heterocyclic carbene
(NHC) precursors (1a-i) and their silver complexes (2a-i) have been synthesized. The Ag (I) …