Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6, CYP2C19, CYP2B6, SLC6A4, and HTR2A Genotypes and Serotonin …

CA Bousman, JM Stevenson… - Clinical …, 2023 - Wiley Online Library
Serotonin reuptake inhibitor antidepressants, including selective serotonin reuptake
inhibitors (SSRIs; ie, citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, and …

Amygdala plasticity and pain

JM Thompson, V Neugebauer - Pain Research and …, 2017 - Wiley Online Library
The amygdala is a limbic brain region that plays a key role in emotional processing,
neuropsychiatric disorders, and the emotional‐affective dimension of pain. Preclinical and …

Neuropathic pain in the community: prevalence, impact, and risk factors

BH Smith, HL Hébert, A Veluchamy - Pain, 2020 - journals.lww.com
Neuropathic pain arises as a direct consequence of a lesion or disease affecting the
somatosensory system. 87 It can be peripheral in origin, as a result of nerve injury or …

The genetics of neuropathic pain from model organisms to clinical application

M Calvo, AJ Davies, HL Hebert, GA Weir, EJ Chesler… - Neuron, 2019 - cell.com
Neuropathic pain (NeuP) arises due to injury of the somatosensory nervous system and is
both common and disabling, rendering an urgent need for non-addictive, effective new …

[HTML][HTML] Pharmacogenetics and pain treatment with a focus on non-steroidal anti-inflammatory drugs (NSAIDs) and antidepressants: a systematic review

F Zobdeh, II Eremenko, MA Akan, VV Tarasov… - Pharmaceutics, 2022 - mdpi.com
Background: This systematic review summarizes the impact of pharmacogenetics on the
effect and safety of non-steroidal anti-inflammatory drugs (NSAIDs) and antidepressants …

Serotonin at the nexus of impulsivity and cue reactivity in cocaine addiction

KA Cunningham, NC Anastasio - Neuropharmacology, 2014 - Elsevier
Cocaine abuse and addiction remain great challenges on the public health agendas in the
US and the world. Increasingly sophisticated perspectives on addiction to cocaine and other …

Advances in the treatment of neuropathic pain

L Xu, Y Zhang, Y Huang - Translational Research in Pain and Itch, 2016 - Springer
Neuropathic pain is pain that arises as a direct consequence of a lesion or diseases
affecting the somatosensory system. Treatments for neuropathic pain include …

Systematic review and meta-analysis of genetic risk factors for neuropathic pain

A Veluchamy, HL Hebert, W Meng, CNA Palmer… - Pain, 2018 - journals.lww.com
Neuropathic pain (NP) is an increasingly common chronic pain state and a major health
burden, affecting approximately 7% to 10% of the general population. Emerging evidence …

Neuropathic pain phenoty** by international consensus (NeuroPPIC) for genetic studies: a NeuPSIG systematic review, Delphi survey, and expert panel …

O Van Hecke, PR Kamerman, N Attal, R Baron… - Pain, 2015 - journals.lww.com
For genetic research to contribute more fully to furthering our knowledge of neuropathic
pain, we require an agreed, valid, and feasible approach to phenoty**, to allow …

5-HT2C receptor knockdown in the amygdala inhibits neuropathic-pain-related plasticity and behaviors

G Ji, W Zhang, L Mahimainathan… - Journal of …, 2017 - jneurosci.org
Neuroplasticity in the amygdala drives pain-related behaviors. The central nucleus (CeA)
serves major amygdala output functions and can generate emotional-affective behaviors …