Streptococcus pneumoniae has a complex relationship with its obligate human host. On the
one hand, the pneumococci are highly adapted commensals, and their main reservoir on the …

Streptococcus pneumoniae (Spn), or the pneumococcus, is a Gram-positive bacterium that
colonizes the upper airway. Spn is an opportunistic pathogen capable of life-threatening …

Teichoic acid (TA), a crucial cell wall constituent of the pathobiont Streptococcus
pneumoniae, is bound to peptidoglycan (wall teichoic acid, WTA) or to membrane …

The molecular basis of the pathogenesis of the opportunistic invasive infections caused by
isolates of the Gemella genus remains largely unknown. Moreover, inconsistencies in the …

Systemic infections with pathogenic or facultative pathogenic bacteria are associated with
activation and aggregation of platelets leading to thrombocytopenia and activation of the …

Wall teichoic acids (WTAs) are charged glycopolymers containing phosphodiester-linked
polyol units and represent one of the major components of Gram-positive cell envelope …

Streptococcus pneumoniae is a Gram-positive opportunistic pathogen that can colonize the
upper respiratory tract. It is a leading cause of a wide range of infectious diseases, including …

Host-to-host transmission is a necessary but poorly understood aspect of microbial
pathogenesis. Herein, we screened a genomic library of mutants of the leading respiratory …

Evolutionarily conserved virulence factors can be candidate therapeutic targets or vaccine
antigens. Here, we investigated the evolutionary selective pressures on 16 pneumococcal …

Streptococcus pneumoniae is a major, encapsulated Gram‐positive pathogen that causes
diseases including community‐acquired pneumonia, meningitis, and sepsis. This pathogen …