Cycles in epilepsy

PJ Karoly, VR Rao, NM Gregg, GA Worrell… - Nature Reviews …, 2021 - nature.com
Epilepsy is among the most dynamic disorders in neurology. A canonical view holds that
seizures, the characteristic sign of epilepsy, occur at random, but, for centuries, humans …

Seizure diaries and forecasting with wearables: epilepsy monitoring outside the clinic

BH Brinkmann, PJ Karoly, ES Nurse… - Frontiers in …, 2021 - frontiersin.org
It is a major challenge in clinical epilepsy to diagnose and treat a disease characterized by
infrequent seizures based on patient or caregiver reports and limited duration clinical …

Forecasting seizure risk in adults with focal epilepsy: a development and validation study

T Proix, W Truccolo, MG Leguia, TK Tcheng… - The Lancet …, 2021 - thelancet.com
Background People with epilepsy are burdened with the apparent unpredictability of
seizures. In the past decade, converging evidence from studies using chronic EEG (cEEG) …

Machine learning and wearable devices of the future

S Beniczky, P Karoly, E Nurse, P Ryvlin, M Cook - Epilepsia, 2021 - Wiley Online Library
Abstract Machine learning (ML) is increasingly recognized as a useful tool in healthcare
applications, including epilepsy. One of the most important applications of ML in epilepsy is …

Ambulatory seizure forecasting with a wrist-worn device using long-short term memory deep learning

M Nasseri, T Pal Attia, B Joseph, NM Gregg… - Scientific reports, 2021 - nature.com
The ability to forecast seizures minutes to hours in advance of an event has been verified
using invasive EEG devices, but has not been previously demonstrated using noninvasive …

Personalized strategies of neurostimulation: from static biomarkers to dynamic closed-loop assessment of neural function

M Carè, M Chiappalone, VR Cota - Frontiers in Neuroscience, 2024 - frontiersin.org
Despite considerable advancement of first choice treatment (pharmacological, physical
therapy, etc.) over many decades, neurological disorders still represent a major portion of …

Neuromodulation in 2035: the neurology future forecasting series

T Denison, MJ Morrell - Neurology, 2022 - neurology.org
Neuromodulation devices are approved in the United States for the treatment of movement
disorders, epilepsy, pain, and depression, and are used off-label for other neurologic …

Seizure forecasting and cyclic control of seizures

RE Stirling, MJ Cook, DB Grayden, PJ Karoly - Epilepsia, 2021 - Wiley Online Library
Epilepsy is a unique neurologic condition characterized by recurrent seizures, where
causes, underlying biomarkers, triggers, and patterns differ across individuals. The …

Noninvasive mobile EEG as a tool for seizure monitoring and management: A systematic review

A Biondi, V Santoro, PF Viana, P Laiou, DK Pal… - …, 2022 - Wiley Online Library
In the last two decades new noninvasive mobile electroencephalography (EEG) solutions
have been developed to overcome limitations of conventional clinical EEG and to improve …

Forecasting seizure likelihood with wearable technology

RE Stirling, DB Grayden, W D'Souza, MJ Cook… - Frontiers in …, 2021 - frontiersin.org
The unpredictability of epileptic seizures exposes people with epilepsy to potential physical
harm, restricts day-to-day activities, and impacts mental well-being. Accurate seizure …