Neurodevelopment is a complex process governed by both intrinsic and extrinsic signals.
While historically studied by researching the brain, inputs from the periphery impact many …

Abstract Development of central nervous system (CNS) is regulated by both intrinsic and
peripheral signals. Previous studies have suggested that environmental factors affect …

1. The blood–brain barrier is essential for the maintenance and regulation of the neural
microenvironment. The main characteristic features of blood–brain barrier endothelial cells …

Brain edema leading to an expansion of brain volume has a crucial impact on morbidity and
mortality following traumatic brain injury (TBI) as it increases intracranial pressure, impairs …

1. Ion permeability of the blood‐brain barrier was studied by in situ measurement of
transendothelial electrical resistance in anaesthetized rats aged between 17 days gestation …

The barrier between the blood and the ventricular cerebrospinal fluid (CSF) is located at the
choroid plexuses. At the interface between two circulating fluids, these richly vascularized …

To evaluate the hypothesis that the proinflammatory cytokines IL-1, IL-6, and tumor necrosis
factor-α might be the link between prenatal intrauterine infection (IUI) and neonatal brain …

Prenatal stress (PS) has been linked to abnormal cognitive, behavioral and psychosocial
outcomes in both animals and humans. Animal studies have clearly demonstrated PS effects …

The gut microbiome has a tremendous influence on human physiology, including the
nervous system. During fetal development, the initial colonization of the microbiome …

The delivery of many potentially therapeutic and diagnostic compounds to specific areas of
the brain is restricted by brain barriers, of which the most well known are the blood–brain …