Most variants associated with complex traits and diseases identified by genome-wide
association studies (GWAS) map to noncoding regions of the genome with unknown effects …

Cardiovascular disease (CVD) is the leading cause of death in women, although
traditionally, it has been considered as a male dominated disease. Chronic inflammation …

Hypertension is one of the leading causes of death due to target organ injury from
cardiovascular disease. Although there are many treatments, only one-sixth of hypertensive …

Innate immunity and chronic inflammation are involved in atherosclerosis and
atherothrombosis, leading to target organ damage in essential hypertension (EH). However …

Naringin is one of the natural flavonoids extracted from many Chinese medicines. It
ameliorates endothelial dysfunctions in atherosclerosis, diabetes, and cardiovascular …

Hypertension is a disease closely related to inflammation, and the systemic immunity-
inflammation index (SII) is a new and easily detectable inflammatory marker. We aimed to …

Background Hypertension is a prevalent cardiovascular disease with severe longer-term
implications. Conventional management based on clinical guidelines does not facilitate …

Background Few studies have estimated the associations of systemic inflammation markers
and high blood pressure (HBP) in the pediatric population. Methods Basing on data from the …

The mycobiome is an essential constituent of the human microbiome and is associated with
various diseases. However, the role of oral and gut fungi in hypertension (HTN) remains …

Hypertension is the leading cause of cardiovascular disease and the primary risk factor for
mortality worldwide. For more than half a century, researchers have demonstrated that …