The ADP-ribosylation factor (ARF) small GTPases regulate vesicular traffic and organelle
structure by recruiting coat proteins, regulating phospholipid metabolism and modulating the …

The Rho GTPases are implicated in almost every fundamental cellular process. They act as
molecular switches that cycle between an active GTP‐bound and an inactive GDP‐bound …

Microtubules and actin filaments are the two main cytoskeleton networks supporting
intracellular architecture and cell polarity. The centrosome nucleates and anchors …

2014-11-12 Assigned to IMMATICS BIOTECHNOLOGIES GMBH reassignment IMMATICS
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …

The composition and identity of cell organelles are dictated by the flux of lipids and proteins
that they receive and lose through cytosolic exchange and membrane trafficking. The trans …

A tendency in cell biology is to divide and conquer. For example, decades of painstaking
work have led to an understanding of endoplasmic reticulum (ER) and Golgi structure …

Trafficking between membrane compartments is a characteristic of eukaryotic cells and
relies on transport carriers that bud and fission from a donor membrane, before being …

The Rho family of small GTPases orchestrates fundamental biological processes such as
cell cycle progression, cell migration, and actin cytoskeleton dynamics, and their aberrant …

Actin filaments play multiple roles in the secretory pathway and in endosome dynamics in
mammals, including maintenance of Golgi structure, release of membrane cargo from the …

Transport carriers regulate membrane flow between compartments of the secretory and
endocytic pathways in eukaryotic cells. Carrier biogenesis is assisted by microtubules, actin …