Brain circuit dysfunction in post-traumatic stress disorder: from mouse to man

RJ Fenster, LAM Lebois, KJ Ressler… - Nature Reviews …, 2018 - nature.com
Post-traumatic stress disorder (PTSD) is a prevalent, debilitating and sometimes deadly
consequence of exposure to severe psychological trauma. Although effective treatments …

Neural contributors to trauma resilience: a review of longitudinal neuroimaging studies

AR Roeckner, KI Oliver, LAM Lebois… - Translational …, 2021 - nature.com
Resilience in the face of major life stressors is changeable over time and with experience.
Accordingly, differing sets of neurobiological factors may contribute to an adaptive stress …

Functional connectivity of amygdala subnuclei in PTSD: a narrative review

EM Haris, RA Bryant, T Williamson… - Molecular …, 2023 - nature.com
While the amygdala is often implicated in the neurobiology of posttraumatic stress disorder
(PTSD), the pattern of results remains mixed. One reason for this may be the heterogeneity …

The neurobiology of emotion regulation in posttraumatic stress disorder: Amygdala downregulation via real‐time fMRI neurofeedback

AA Nicholson, D Rabellino, M Densmore… - Human Brain …, 2017 - Wiley Online Library
Amygdala dysregulation has been shown to be central to the pathophysiology of
posttraumatic stress disorder (PTSD) representing a critical treatment target. Here, amygdala …

A 12‐week integrative exercise program improves self‐reported mindfulness and interoceptive awareness in war veterans with posttraumatic stress symptoms

WE Mehling, MA Chesney, TJ Metzler… - Journal of clinical …, 2018 - Wiley Online Library
Objective Innovative approaches to the treatment of war‐related posttraumatic stress
disorder (PTSD) are needed. We report on secondary psychological outcomes of a …

MRI findings in posttraumatic stress disorder

A Kunimatsu, K Yasaka, H Akai… - Journal of Magnetic …, 2020 - Wiley Online Library
Posttraumatic stress disorder (PTSD) is a psychiatric condition that develops after a person
experiences one or more traumatic events, characterized by intrusive recollection …

How processing of sensory information from the internal and external worlds shape the perception and engagement with the world in the aftermath of trauma …

S Harricharan, MC McKinnon, RA Lanius - Frontiers in Neuroscience, 2021 - frontiersin.org
Post-traumatic stress disorder (PTSD) is triggered by an individual experiencing or
witnessing a traumatic event, often precipitating persistent flashbacks and severe anxiety …

Synaptic loss and the pathophysiology of PTSD: implications for ketamine as a prototype novel therapeutic

JH Krystal, CG Abdallah, LA Averill, B Kelmendi… - Current psychiatry …, 2017 - Springer
Abstract Purpose of Review Studies of the neurobiology and treatment of PTSD have
highlighted many aspects of the pathophysiology of this disorder that might be relevant to …

A review of the neurobiological basis of trauma-related dissociation and its relation to cannabinoid-and opioid-mediated stress response: A transdiagnostic …

RA Lanius, JE Boyd, MC McKinnon… - Current Psychiatry …, 2018 - Springer
Dissociative experiences have been associated with increased disease severity, chronicity,
and, in some cases, reduced treatment response across trauma-related and other …

The cerebellum after trauma: Resting‐state functional connectivity of the cerebellum in posttraumatic stress disorder and its dissociative subtype

D Rabellino, M Densmore, J Théberge… - Human brain …, 2018 - Wiley Online Library
The cerebellum plays a key role not only in motor function but also in affect and cognition.
Although several psychopathological disorders have been associated with overall …