Treatment with psychedelics is psychotherapy: beyond reductionism

G Gründer, M Brand, LJ Mertens, H Jungaberle… - The Lancet …, 2024‏ - thelancet.com
Treatment of psychiatric disorders with psychedelic substances represents one of the most
promising current treatment approaches in psychiatry. Since its inception in the 1950s …

The Altered States Database: Psychometric data from a systematic literature review

J Prugger, E Derdiyok, J Dinkelacker, C Costines… - Scientific data, 2022‏ - nature.com
In this paper, we present the development of the Altered States Database (ASDB), an open-
science project based on a systematic literature review. The ASDB contains psychometric …

Transformative experience and informed consent to psychedelic-assisted psychotherapy

E Jacobs - Frontiers in Psychology, 2023‏ - frontiersin.org
Just as psychedelic-assisted psychotherapy (PAP) represents a clinical innovation that may
need to be accommodated with corresponding theoretical and methodological innovations …

Therapeutic alliance and rapport modulate responses to psilocybin assisted therapy for depression

R Murphy, H Kettner, R Zeifman, B Giribaldi… - Frontiers in …, 2022‏ - frontiersin.org
Background: Across psychotherapeutic frameworks, the strength of the therapeutic alliance
has been found to correlate with treatment outcomes; however, its role has never been …

Compassion as a skill: A comparison of contemplative and evolution-based approaches

P Gilbert, W Van Gordon - Mindfulness, 2023‏ - Springer
The editors to this volume posed a series of fascinating questions relating to how seeing
compassion as a skill can help us understand its nature, cultivation and effects within …

Pattern breaking: a complex systems approach to psychedelic medicine

I Hipólito, J Mago, FE Rosas… - Neuroscience of …, 2023‏ - academic.oup.com
Recent research has demonstrated the potential of psychedelic therapy for mental health
care. However, the psychological experience underlying its therapeutic effects remains …

A framework for assessment of adverse events occurring in psychedelic-assisted therapies

R Palitsky, DM Kaplan, J Perna… - Journal of …, 2024‏ - journals.sagepub.com
Objective: Despite considerable research examining the efficacy of psychedelic-assisted
therapies (PATs) for treating psychiatric disorders, assessment of adverse events (AEs) in …

Measuring psychotherapeutic processes in the context of psychedelic experiences: Validation of the General Change Mechanisms Questionnaire (GCMQ)

M Wolff, R Evens, LJ Mertens… - Journal of …, 2024‏ - journals.sagepub.com
Background: Therapeutic and salutogenic effects of psychedelic drugs have been attributed
to psychotherapeutic or psychotherapy-like processes that can unfold during the acute …

Distinctive but not exceptional: The risks of psychedelic ethical exceptionalism

K Cheung, BD Earp, K Patch… - The American Journal of …, 2025‏ - Taylor & Francis
When used clinically, psychedelics may appear unusual or even unique when compared to
more familiar or long-standing medical interventions, prompting some to suggest that the …

Targeting metaplasticity mechanisms to promote sustained antidepressant actions

KA Brown, TD Gould - Molecular psychiatry, 2024‏ - nature.com
The discovery that subanesthetic doses of (R, S)-ketamine (ketamine) and (S)-ketamine
(esketamine) rapidly induce antidepressant effects and promote sustained actions following …