Aspergillus fumigatus melanins: interference with the host endocytosis pathway and impact on virulence

T Heinekamp, A Thywißen, J Macheleidt… - Frontiers in …, 2013 - frontiersin.org
The opportunistic human pathogenic fungus Aspergillus fumigatus produces at least two
types of melanin, namely pyomelanin and dihydroxynaphthalene (DHN) melanin …

On the lineage of Aspergillus fumigatus isolates in common laboratory use

M Bertuzzi, N Van Rhijn, S Krappmann… - Medical …, 2021 - academic.oup.com
The origin of isolates routinely used by the community of Aspergillus fumigatus researchers
is periodically a matter of intense discussion at our centre, as the construction of …

The Biotrophic Development of Ustilago maydis Studied by RNA-Seq Analysis

D Lanver, AN Müller, P Happel, G Schweizer… - The Plant …, 2018 - academic.oup.com
The maize smut fungus Ustilago maydis is a model organism for elucidating host
colonization strategies of biotrophic fungi. Here, we performed an in depth transcriptional …

Amino acid utilization allows intestinal dominance of Lactobacillus amylovorus

Y **g, C Mu, H Wang, J Shen, EG Zoetendal… - The ISME …, 2022 - academic.oup.com
The mammalian intestine harbors heterogeneous distribution of microbes among which
specific taxa (eg Lactobacillus) dominate across mammals. Deterministic factors such as …

The pH-Responsive PacC Transcription Factor of Aspergillus fumigatus Governs Epithelial Entry and Tissue Invasion during Pulmonary Aspergillosis

M Bertuzzi, M Schrettl, L Alcazar-Fuoli, TC Cairns… - PLoS …, 2014 - journals.plos.org
Destruction of the pulmonary epithelium is a major feature of lung diseases caused by the
mould pathogen Aspergillus fumigatus. Although it is widely postulated that tissue invasion …

Metabolism in fungal pathogenesis

IV Ene, S Brunke, AJP Brown… - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
Fungal pathogens must assimilate local nutrients to establish an infection in their
mammalian host. We focus on carbon, nitrogen, and micronutrient assimilation mechanisms …

Azole-induced cell wall carbohydrate patches kill Aspergillus fumigatus

B Geißel, V Loiko, I Klugherz, Z Zhu, N Wagener… - Nature …, 2018 - nature.com
Azole antifungals inhibit the fungal ergosterol biosynthesis pathway, resulting in either
growth inhibition or killing of the pathogen, depending on the species. Here we report that …

[HTML][HTML] Turning inside out: Filamentous fungal secretion and its applications in biotechnology, agriculture, and the clinic

TC Cairns, X Zheng, P Zheng, J Sun, V Meyer - Journal of Fungi, 2021 - mdpi.com
Filamentous fungi are found in virtually every marine and terrestrial habitat. Vital to this
success is their ability to secrete a diverse range of molecules, including hydrolytic enzymes …

Induction and Repression of Hydrolase Genes in Aspergillus oryzae

M Tanaka, K Gomi - Frontiers in microbiology, 2021 - frontiersin.org
The filamentous fungus Aspergillus oryzae, also known as yellow koji mold, produces high
levels of hydrolases such as amylolytic and proteolytic enzymes. This property of producing …

Role of amino acid metabolism in the virulence of human pathogenic fungi

E Garbe, S Vylkova - Current Clinical Microbiology Reports, 2019 - Springer
Abstract Purpose of the Review The success of Candida albicans, Aspergillus fumigatus,
and Cryptococcus neoformans as fungal pathogens depends on their rapid adaptation to …