Although there is now an extensive understanding of the diversity of microbial life on earth
through culture-independent metagenomic DNA sequence analyses, the isolation and …

Peptides are biopolymers, typically consisting of 2–50 amino acids. They are biologically
produced by the cellular ribosomal machinery or by non-ribosomal enzymes and …

Metagenome-based resources have revealed the diversity and function of the human gut
microbiome, but further understanding is limited by insufficient genome quality and a lack of …

The growing problem of antibiotic resistance has led to the exploration of uncultured
bacteria as potential sources of new antimicrobials. PCR amplicon analyses and short-read …

The increase in microbial sequenced genomes from pure cultures and metagenomic
samples reflects the current attainability of whole-genome and shotgun sequencing …

Authored by leading experts in the enzymology of natural product biosynthesis, this textbook
provides a thorough description of the types of natural products, the biosynthetic pathways …

The rapid industrial and economic development runs on fossil fuel and other energy
sources. Limited oil reserves, environmental issues, and high transportation costs lead …

The gut microbiome is a major determinant of host health, yet it is only in the last 2 decades
that the advent of next-generation sequencing has enabled it to be studied at a genomic …

Multi-locus sequence analysis (MLSA) has been proved to be a useful method for
Streptomyces identification and MLSA distance of 0.007 is considered as the boundary …

Abstract Background Wastewater treatment plants (WWTPs) are one of the largest
biotechnology applications in the world and are of critical importance to modern urban …