Recent work has shown that acidocalcisomes, which are electron-dense acidic organelles
rich in calcium and polyphosphate, are the only organelles that have been conserved during …

The Trypanosomatidae comprise a large group of parasitic protozoa, some of which cause
important diseases in humans. These include Trypanosoma brucei (the causative agent of …

Acidocalcisomes are acidic organelles containing calcium and a high concentration of
phosphorus in the form of pyrophosphate (PPi) and polyphosphate (poly P). Organelles with …

Toxoplasma gondii belongs to the phylum Apicomplexa and is an important cause of
congenital disease and infection in immunocompromised patients. Like most …

Vacuolar-type H+-translocating inorganic pyrophosphatases have long been considered to
be restricted to plants and to a few species of phototrophic bacteria. However, in recent …

We report the cloning and sequencing of a gene encoding the farnesyl pyrophosphate
synthase of Trypanosoma cruzi. The protein (T. cruzi farnesyl pyrophosphate synthase …

Acidocalcisomes are acidic calcium storage compartments described in several unicellular
eukaryotes, including trypanosomatid and apicomplexan parasites, algae, and slime molds …

The acidocalcisome is an electron-dense acidic organelle which contains a matrix of
pyrophosphate and polyphosphates with bound calcium and other cations. Its limiting …

Acidocalcisomes are organelles conserved during evolution and closely related to the so-
called volutin granules of bacteria and archaea, to the acidocalcisome-like vacuoles of …

We cloned an aquaporin gene from Trypanosoma cruzi (TcAQP) that encodes a protein of
231 amino acids, which is highly hydrophobic. The protein has six putative transmembrane …