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TGF-β in radiotherapy: Mechanisms of tumor resistance and normal tissues injury
Emerging evidences show that changes in tumor stroma can adapt cancer cells to
radiotherapy, thereby leading to a reduction in tumor response to treatment. On the other …
radiotherapy, thereby leading to a reduction in tumor response to treatment. On the other …
Radiation‐induced myocardial fibrosis: mechanisms underlying its pathogenesis and therapeutic strategies
B Wang, H Wang, M Zhang, R Ji, J Wei… - Journal of Cellular …, 2020 - Wiley Online Library
Radiation‐induced myocardial fibrosis (RIMF) is a potentially lethal clinical complication of
chest radiotherapy (RT) and a final stage of radiation‐induced heart disease (RIHD). RIMF is …
chest radiotherapy (RT) and a final stage of radiation‐induced heart disease (RIHD). RIMF is …
COX-2 in liver fibrosis
H Yang, Y Xuefeng, W Shandong, X Jianhua - Clinica chimica acta, 2020 - Elsevier
As a vital inducible sensor, cyclooxygenase-2 (COX-2) plays an important role in the
progress of hepatic fibrogenesis. Activation of hepatic stellate cells (HSCs) in the liver can …
progress of hepatic fibrogenesis. Activation of hepatic stellate cells (HSCs) in the liver can …
Paracrine effects of human amniotic epithelial cells protect against chemotherapy-induced ovarian damage
Q Zhang, S Bu, J Sun, M Xu, X Yao, K He… - Stem cell research & …, 2017 - Springer
Background Human amniotic epithelial cells (hAECs) are attractive candidates for
regenerative medical therapy, with the potential to replace deficient cells and improve …
regenerative medical therapy, with the potential to replace deficient cells and improve …
Inflammatory mediators in oral cancer: pathogenic mechanisms and diagnostic potential
SE Niklander - Frontiers in Oral Health, 2021 - frontiersin.org
Approximately 15% of cancers are attributable to the inflammatory process, and growing
evidence supports an association between oral squamous cell carcinoma (OSCC) and …
evidence supports an association between oral squamous cell carcinoma (OSCC) and …
TGF-β1 induces VEGF expression in human granulosa-lutein cells: a potential mechanism for the pathogenesis of ovarian hyperstimulation syndrome
Ovarian hyperstimulation syndrome (OHSS) is one of the most serious and iatrogenic
complications that can occur during in vitro fertilization treatment. Although the pathogenesis …
complications that can occur during in vitro fertilization treatment. Although the pathogenesis …
Transforming growth factor-β is involved in maintaining oocyte meiotic arrest by promoting natriuretic peptide type C expression in mouse granulosa cells
J Yang, Y Zhang, X Xu, J Li, F Yuan, S Bo, J Qiao… - Cell Death & …, 2019 - nature.com
Natriuretic peptide type C (NPPC) secreted by mural granulosa cells (MGCs) maintains
oocyte meiotic arrest via the activation of guanylyl cyclase-linked natriuretic peptide receptor …
oocyte meiotic arrest via the activation of guanylyl cyclase-linked natriuretic peptide receptor …
Canine placenta: a source of prepartal prostaglandins during normal and antiprogestin-induced parturition
MP Kowalewski, HB Beceriklisoy, C Pfarrer… - …, 2010 - rep.bioscientifica.com
Expression of cyclooxygenase 2 (COX2, now known as PTGS2), prostaglandin E2 synthase
(PTGES, PGES), and prostaglandin F2α synthase (PGFS), of the respective receptors …
(PTGES, PGES), and prostaglandin F2α synthase (PGFS), of the respective receptors …
Role of transforming growth factor-β in muscle damage and regeneration: focused on eccentric muscle contraction
J Kim, J Lee - Journal of exercise rehabilitation, 2017 - pmc.ncbi.nlm.nih.gov
High-intensity eccentric muscle contraction induces muscle damage. Damaged muscles
recover through different processes, including degeneration, inflammation, regeneration …
recover through different processes, including degeneration, inflammation, regeneration …
TGF-β1 downregulates StAR expression and decreases progesterone production through Smad3 and ERK1/2 signaling pathways in human granulosa cells
Context: Regulation of progesterone production in granulosa cells is important for normal
reproductive functions. Steroidogenic acute regulatory protein (StAR) is recognized as the …
reproductive functions. Steroidogenic acute regulatory protein (StAR) is recognized as the …